novobiocin - CISMeF

Preferred Label : novobiocin;

MeSH definition : An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189);

MeSH synonym : streptonivicin; crystallinic acid;

CISMeF synonym : 1476-53-5 (Novobiocin sodium); 4309-70-0 (Novobiocin calcium);

MeSH hyponym : Novobiocin Calcium; Novobiocin Sodium; Calcium, Novobiocin; Sodium, Novobiocin; Novobiocin, Monosodium Salt; Monosodium Salt Novobiocin;

MeSH CAS label : benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-;

MeSH Related Number : novobiocin calcium; novobiocin sodium; 1476-53-5 (mono-Na salt); 303-81-1 (Novobiocin); 4309-70-0 (Ca salt); Q9S9NQ5YIY; RHW5BU180N;

Registry Number MeSH : 303-81-1;

Related CAS MeSH : RHW5BU180N (Novobiocin calcium); Q9S9NQ5YIY (Novobiocin sodium);

Wikipedia link : https://en.wikipedia.org/wiki/Novobiocin;

Codes EINECS : 206-146-3;

Is substance : O;

UNII : 17EC19951N;

InChIKey : YJQPYGGHQPGBLI-KGSXXDOSSA-N;

Details

Origin ID

D009675;

UMLS CUI

C0028458;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Novobiocin [ICHI extension code]
- Novobiocin Calcium [NCIt concept]
- Novobiocin Sodium [NCIt concept]
- Novobiocin sodium (substance) [SNOMED CT concept]
- Streptonivicin [ICHI extension code]
- novobiocin calcium [Substance BNPC]
- novobiocin sodium [SNOMED Notion]
CISMeF manual mappings
- novobiocin [Substance BNPC]
Currated CISMeF NLP mapping
- Novobiocin [ICD-11 Extension code]
- Novobiocin [LOINC component]
- Novobiocin [NCIt concept]
- Novobiocin (substance) [SNOMED CT concept]
- Product containing novobiocin (medicinal product) [SNOMED CT concept]
- novobiocin [SNOMED Notion]
Pharmacological action(s)
- anti-bacterial agents [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- Novobiocin Calcium [MeSH concept]
- Novobiocin Sodium [MeSH concept]
- novobiocin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2''-O-carbamylnovobiocin [MeSH Supplementary Concept]
- 4-tosylcyclonovobiocic acid [MeSH Supplementary Concept]
- 7-tosylcyclonovobiocic acid [MeSH Supplementary Concept]
- KU-32 compound [MeSH Supplementary Concept]
- KU135 [MeSH Supplementary Concept]
- TPU-0031-A [MeSH Supplementary Concept]
- TPU-0031-B [MeSH Supplementary Concept]
- albacillin [MeSH Supplementary Concept]
- albamycin T [MeSH Supplementary Concept]
- antibiotic 2562 [MeSH Supplementary Concept]
- clorobiocin [MeSH Supplementary Concept]
- descarbamylnovobiocin [MeSH Supplementary Concept]
- dihydronovobiocin [MeSH Supplementary Concept]
- isonovobiocin [MeSH Supplementary Concept]
- novclobiocin 101 [MeSH Supplementary Concept]
- novclobiocin 102 [MeSH Supplementary Concept]
- novclobiocin 114 [MeSH Supplementary Concept]
- novenamine [MeSH Supplementary Concept]
- novobiocin 401 [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Streptonivicin [ICD-11 Extension code]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Novobiocin [ICD-11 Extension code]
- Novobiocin [NCIt concept]
- Novobiocin [LOINC component]
- Novobiocin (substance) [SNOMED CT concept]
- Product containing novobiocin (medicinal product) [SNOMED CT concept]
- novobiocin [Substance BNPC]
- novobiocin [SNOMED Notion]
Validated automatic mappings to BTNT
- Novobiocin Calcium [NCIt concept]
- Novobiocin Sodium [NCIt concept]
- Novobiocin sodium (substance) [SNOMED CT concept]
- novobiocin calcium [Substance BNPC]
- novobiocin sodium [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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