Preferred Label : novobiocin;
MeSH definition : An antibiotic compound derived from Streptomyces niveus. It has a chemical structure
similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase
(ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189);
MeSH synonym : streptonivicin; crystallinic acid;
CISMeF synonym : 1476-53-5 (Novobiocin sodium); 4309-70-0 (Novobiocin calcium);
MeSH hyponym : Novobiocin Calcium; Novobiocin Sodium; Calcium, Novobiocin; Sodium, Novobiocin; Novobiocin, Monosodium Salt; Monosodium Salt Novobiocin;
MeSH CAS label : benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-;
MeSH Related Number : novobiocin calcium; novobiocin sodium; 1476-53-5 (mono-Na salt); 303-81-1 (Novobiocin); 4309-70-0 (Ca salt); Q9S9NQ5YIY; RHW5BU180N;
Registry Number MeSH : 303-81-1;
Related CAS MeSH : RHW5BU180N (Novobiocin calcium); Q9S9NQ5YIY (Novobiocin sodium);
Wikipedia link : https://en.wikipedia.org/wiki/Novobiocin;
Codes EINECS : 206-146-3;
Is substance : O;
UNII : 17EC19951N;
InChIKey : YJQPYGGHQPGBLI-KGSXXDOSSA-N;
Origin ID : D009675;
UMLS CUI : C0028458;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- KU135 [MeSH Supplementary Concept]
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
An antibiotic compound derived from Streptomyces niveus. It has a chemical structure
similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase
(ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)