interferon-alpha

Preferred Label : interferon-alpha;

MeSH definition : One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.;

MeSH synonym : interferon, lymphoblastoid; alpha-interferon; interferon, lymphoblast; interferon, leukocyte; lymphoblastoid interferon; leukocyte interferon; interferon alfa; lymphoblast interferon; alpha interferon; interferon alpha; interferon, alpha;

CISMeF synonym : glaxo wellcome brand of interferon alfa n1; interferon alfa n3; D, leif; 2, interferon-alpha; IFN-alpha 2; IFN-alpha-2; LeIF A; interferon alpha 2; interferon alpha A; interferon alpha-A; interferon-alpha 2;

MeSH hyponym : interferon alpha-17; interferon alpha-5; interferon alpha-4; interferon alpha-1; interferon alpha-7; Interferon alpha 17; Interferon alpha-T; Interferon alpha T; Interferon alpha-88; Interferon alpha 88; LeIF I; Interferon alpha 5; Interferon alpha5; IFN-alpha5; IFN alpha5; Interferon alpha 7; LeIF J; Interferon alpha-J; Interferon alpha J; Interferon alpha 1; IFN-alpha D; IFN alpha D; Leif D; Interferon alpha 4; Interferon alpha4;

Wikipedia link : https://en.wikipedia.org/wiki/Alpha-interferon;

Is substance : O;

Details

Origin ID

D016898;

UMLS CUI

C0002199;

ATC code(s)
- interferon alfa natural [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Interferon Alfa-N1 [NCIt concept]
- Interferon Alpha [NCIt concept]
- Interferon alfa [ICD-11 Extension code]
- Interferon alfa [SMS substance]
- Interferon alfa (substance) [SNOMED CT concept]
- Interferon alpha [LOINC component]
- Product containing interferon alfa (product) [SNOMED CT concept]
- Recombinant Interferon Alfa [NCIt concept]
- alpha interferon [SNOMED Notion]
- interferon alpha [COVID-19 Thesaurus concept]
Indexing information
- albumin interferon [MeSH Supplementary Concept]
Pharmacological action(s)
- antiviral agents [MeSH Descriptor]
- immunologic factors [MeSH Descriptor]
Record concept(s)
- interferon alpha-1 [MeSH concept]
- interferon alpha-17 [MeSH concept]
- interferon alpha-4 [MeSH concept]
- interferon alpha-5 [MeSH concept]
- interferon alpha-7 [MeSH concept]
- interferon-alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- (Gly)2-interferon alpha2b(122-137)-Gly(138)-Gly(139)-interferon alpha2b(30-35)-(Gly)2 [MeSH Supplementary Concept]
- CHVP regimen [MeSH Supplementary Concept]
- DAI protocol [MeSH Supplementary Concept]
- IFN-alpha21a(1-75), IFN-alpha2c(76-165) fusion protein [MeSH Supplementary Concept]
- IFN-alpha21a(1-95), IFN-alpha2c(96-165) fusion protein [MeSH Supplementary Concept]
- IFNA1 protein, human [MeSH Supplementary Concept]
- IFNA10 protein, human [MeSH Supplementary Concept]
- IFNA13 protein, human [MeSH Supplementary Concept]
- IFNA14 protein, human [MeSH Supplementary Concept]
- IFNA16 protein, human [MeSH Supplementary Concept]
- IFNA17 protein, human [MeSH Supplementary Concept]
- IFNA2 protein, human [MeSH Supplementary Concept]
- IFNA21 protein, human [MeSH Supplementary Concept]
- IFNA4 protein, human [MeSH Supplementary Concept]
- IFNA5 protein, human [MeSH Supplementary Concept]
- IFNA6 protein, human [MeSH Supplementary Concept]
- IFNA7 protein, human [MeSH Supplementary Concept]
- IFNA8 protein, human [MeSH Supplementary Concept]
- Ifna1 protein, mouse [MeSH Supplementary Concept]
- Ifna10 protein, mouse [MeSH Supplementary Concept]
- Ifna12 protein, mouse [MeSH Supplementary Concept]
- Ifna13 protein, mouse [MeSH Supplementary Concept]
- Ifna14 protein, mouse [MeSH Supplementary Concept]
- Ifna2 protein, mouse [MeSH Supplementary Concept]
- Ifna3 protein, mouse [MeSH Supplementary Concept]
- Ifna6 protein, mouse [MeSH Supplementary Concept]
- Ifna9 protein, mouse [MeSH Supplementary Concept]
- Ifrg15 protein, mouse [MeSH Supplementary Concept]
- Interferon-alpha2b [MeSH Supplementary Concept]
- PEG-IFN-SA [MeSH Supplementary Concept]
- PF-04849285 [MeSH Supplementary Concept]
- PFLI-alpha protocol [MeSH Supplementary Concept]
- PIAF regimen [MeSH Supplementary Concept]
- ROAD-IN protocol [MeSH Supplementary Concept]
- albinterferon alfa-2b [MeSH Supplementary Concept]
- albuferon [MeSH Supplementary Concept]
- combiferon [MeSH Supplementary Concept]
- cyclo((Gly)2-interferon alpha2b(122-137)-Gly(138)-Gly(139)-interferon alpha2b(30-35)-(Gly)2) [MeSH Supplementary Concept]
- cytoferon [MeSH Supplementary Concept]
- human serum albumin-interferon-alpha-2b fusion protein [MeSH Supplementary Concept]
- ifna protein, mouse [MeSH Supplementary Concept]
- interferon Alfa-n3 [MeSH Supplementary Concept]
- interferon alfa-1b, human [MeSH Supplementary Concept]
- interferon alfa-2c [MeSH Supplementary Concept]
- interferon alfa-n1 [MeSH Supplementary Concept]
- interferon alfacon-1 [MeSH Supplementary Concept]
- interferon alpha 2, Ala(30,32,33)- [MeSH Supplementary Concept]
- interferon alpha 4A [MeSH Supplementary Concept]
- interferon alpha, HY-3 [MeSH Supplementary Concept]
- interferon, alfa 2(125-129) [MeSH Supplementary Concept]
- interferon, alpha 1(111-166) [MeSH Supplementary Concept]
- interferon, alpha 2(1-110) [MeSH Supplementary Concept]
- interferon, alpha 2(111-153) [MeSH Supplementary Concept]
- interferon-alfa-1b [MeSH Supplementary Concept]
- interferon-alpha 8 [MeSH Supplementary Concept]
- interferon-alpha A-D [MeSH Supplementary Concept]
- interferon-alpha B-D [MeSH Supplementary Concept]
- interferon-alpha, immunoglobulin-linked [MeSH Supplementary Concept]
- methionyl human consensus alpha interferon [MeSH Supplementary Concept]
- peginterferon alfa-2a [MeSH Supplementary Concept]
- peginterferon alfa-2b [MeSH Supplementary Concept]
- peptide 2438 [MeSH Supplementary Concept]
- rebetron [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Interferon alfa (substance) [SNOMED CT concept]
- Interferon alpha [LOINC component]
- Product containing interferon alfa (product) [SNOMED CT concept]
- alpha interferon [SNOMED Notion]
- interferon alfa natural [ATC Code]
Validated automatic mappings to BTNT
- Interferon alfa-n1 (substance) [SNOMED CT concept]
- interferon alfa natural [ATC Code]
- interferon alfa-n1 [ATC Code]

Keyword's position in hierarchy(ies) :

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