receptor, interferon alpha-beta

Preferred Label : receptor, interferon alpha-beta;

MeSH definition : A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.;

MeSH synonym : alpha receptors, interferon; interferon alpha receptor; interferon alpha receptors; interferon alphabeta receptors; receptor, interferon alpha; type i interferon receptor; ifn-alphar; alpha receptor, interferon; interferon alpha-beta receptor; interferon alpha beta receptor; receptors, interferon alphabeta; ifn-alphabetar; ifn alphabetar; receptors, interferon alpha; receptor, interferon alpha beta;

MeSH hyponym : IFNAR2.2 subunit, interferon alpha-beta receptor; interferon alpha-beta receptor chain 1; IFNAR2.1 subunit, interferon alpha-beta receptor; interferon alpha-beta receptor chain 2; Interferon alpha beta Receptor Chain 2; Interferon alpha-beta Receptor IFNAR2 Subunit; Interferon alpha beta Receptor IFNAR2 Subunit; Interferon alpha-beta Receptor-2; Interferon alpha beta Receptor 2; Receptor-2, Interferon alpha-beta; alpha-beta Receptor-2, Interferon; IFNAR2 Subunit, Interferon alpha-beta Receptor; IFNAR2 Subunit, Interferon alpha beta Receptor; Interferon alpha beta Receptor Chain 1; Interferon alpha-beta Receptor IFNAR1 Subunit; Interferon alpha beta Receptor IFNAR1 Subunit; Interferon alpha-beta Receptor-1; Interferon alpha beta Receptor 1; Receptor-1, Interferon alpha-beta; alpha-beta Receptor-1, Interferon; IFNAR1 Subunit, Interferon alpha-beta Receptor; IFNAR1 Subunit, Interferon alpha beta Receptor; IFNAR2.1 Subunit, Interferon alpha beta Receptor; IFNAR2.2 Subunit, Interferon alpha beta Receptor;

Registry Number MeSH : 156986-95-7;

Is substance : O;

Details

Origin ID

D053633;

UMLS CUI

C0254653;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Record concept(s)
- IFNAR2.1 subunit, interferon alpha-beta receptor [MeSH concept]
- IFNAR2.2 subunit, interferon alpha-beta receptor [MeSH concept]
- interferon alpha-beta receptor chain 1 [MeSH concept]
- interferon alpha-beta receptor chain 2 [MeSH concept]
- receptor, interferon alpha-beta [MeSH concept]
Related MeSH Supplementary Concept(s)
- IFNAR1 protein, human [MeSH Supplementary Concept]
- IFNAR2 protein, human [MeSH Supplementary Concept]
- Ifnar1 protein, mouse [MeSH Supplementary Concept]
- Ifnar2 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
Validated automatic mappings to BTNT
- Interferon Alpha/Beta Receptor 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients