rifampin - CISMeF

Preferred Label : rifampin;

MeSH definition : A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160);

MeSH synonym : rifampicin; benemycin;

MeSH hyponym : rimactane; rimactan; tubocin; rifadin;

MeSH CAS label : rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-;

MeSH Related Number : 13292-46-1 (Rifampin);

Registry Number MeSH : 13292-46-1;

Wikipedia link : https://en.wikipedia.org/wiki/Rifampicin;

Codes EINECS : 236-312-0;

Is substance : O;

UNII : VJT6J7R4TR;

InChIKey : JQXXHWHPUNPDRT-WLSIYKJHSA-N;

Details

Origin ID

D012293;

UMLS CUI

C0035608;

ATC code(s)
- dapsone and rifampicin [ATC Code]
- dapsone, rifampicin and clofazimine [ATC Code]
- rifampicin [ATC Code]
- rifampicin and isoniazid [ATC Code]
- rifampicin, ethambutol and isoniazid [ATC Code]
- rifampicin, pyrazinamide and isoniazid [ATC Code]
- rifampicin, pyrazinamide, ethambutol and isoniazid [ATC Code]
- rifampicin, pyrazinamide, isoniazid and levofloxacin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Rifampicin (substance) [SNOMED CT concept]
- Rifampicin poisoning (disorder) [SNOMED CT concept]
- Urine rifampicin level (procedure) [SNOMED CT concept]
- rifampicin [Substance BNPC]
Exact mapping(s) to DCI
- Rifampin [International Nonproprietary Name]
Manual BTNT mappings - CISMeF
- Rifampin sodium [International Nonproprietary Name]
Pharmacological action(s)
- Cytochrome P-450 CYP2B6 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2C19 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2C8 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2C9 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP3A Inducers [MeSH Descriptor]
- Metabolic Side Effects of Drugs and Substances [MeSH Descriptor]
- antibiotics, antitubercular [MeSH Descriptor]
- leprostatic agents [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- rifadin [MeSH concept]
- rifampin [MeSH concept]
- rimactan [MeSH concept]
- rimactane [MeSH concept]
- tubocin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 18,19-dihydrorifampicin [MeSH Supplementary Concept]
- 21-(O-phosphoryl)rifampicin [MeSH Supplementary Concept]
- 23-(O-(beta-glucopyranosyl))rifampicin [MeSH Supplementary Concept]
- 23-(O-ribofuranosyl)rifampicin [MeSH Supplementary Concept]
- 25-deacetylrifampicin [MeSH Supplementary Concept]
- 25-desacetylrifapentine [MeSH Supplementary Concept]
- 3-formyl-21-(O-phosphoryl)rifamycin SV [MeSH Supplementary Concept]
- 3-formyl-23-(O-(beta-glucopyranosyl))rifamycin SV [MeSH Supplementary Concept]
- 3-formyl-23-(O-ribofuranosyl)rifamycin SV [MeSH Supplementary Concept]
- CGP 43371 [MeSH Supplementary Concept]
- CGS 24565 [MeSH Supplementary Concept]
- DMB-rifampicin [MeSH Supplementary Concept]
- KSV21 compound [MeSH Supplementary Concept]
- cotrifazid [MeSH Supplementary Concept]
- dehydrorifampicin [MeSH Supplementary Concept]
- isoniazid, pyrazinamide, rifampin drug combination [MeSH Supplementary Concept]
- myrin P [MeSH Supplementary Concept]
- rifamazid [MeSH Supplementary Concept]
- rifampicin N-oxide [MeSH Supplementary Concept]
- rifapentine [MeSH Supplementary Concept]
- rifaprim [MeSH Supplementary Concept]
- rivicycline [MeSH Supplementary Concept]
- sinerdol EH [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing rifampicin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing rifampicin (medicinal product) [SNOMED CT concept]
- Rifampicin [ICD-11 Extension code]
- Rifampicin (substance) [SNOMED CT concept]
- Rifampin [International Nonproprietary Name]
- Rifampin [NCIt concept]
- rifAMPin [LOINC component]
- rifampicin [ATC Code]
- rifampicin [Substance BNPC]
- rifampin [SNOMED Notion]
Validated automatic mappings to BTNT
- Rifampicin sodium [SMS substance]
- Rifampin sodium [International Nonproprietary Name]
- rifampicin [ATC Code]
Validated automatic mappings to NTBT
- Rifampicins [Bloc CIM-11]

Keyword's position in hierarchy(ies) :

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