mitomycin - CISMeF

Preferred Label : mitomycin;

MeSH definition : An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.;

MeSH synonym : mitomycin-c; mitomycin c;

MeSH hyponym : ametycine; mutamycin; Mitocin-C; NSC-26980; Mitocin C; MitocinC; NSC 26980; NSC26980;

MeSH CAS label : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-;

MeSH Related Number : 50-07-7 (Mitomycin); 69515-74-8 ((1aalpha,8beta,8aalpha,8balpha)-isomer);

Registry Number MeSH : 50-07-7;

MeSH annotation : MITOMYCINS is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Mutamycin;

Is substance : O;

UNII : 50SG953SK6;

InChIKey : NWIBSHFKIJFRCO-WUDYKRTCSA-N;

Details

Origin ID

D016685;

UMLS CUI

C0002475;

ATC code(s)
- mitomycin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Mitomycin Antineoplastic Antibiotic [NCIt concept]
Currated CISMeF NLP mapping
- Mitomycin [ICD-11 Extension code]
- Mitomycin [ICHI extension code]
- Mitomycin [SMS substance]
- Mitomycin [NCIt concept]
- Mitomycin (substance) [SNOMED CT concept]
- mitomycin [SNOMED Notion]
Pharmacological action(s)
- alkylating agents [MeSH Descriptor]
- antibiotics, antineoplastic [MeSH Descriptor]
- cross-linking reagents [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- Mitocin-C [MeSH concept]
- NSC-26980 [MeSH concept]
- ametycine [MeSH concept]
- mitomycin [MeSH concept]
- mutamycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- AVM protocol [MeSH Supplementary Concept]
- BEMP protocol 2 [MeSH Supplementary Concept]
- BLM-M protocol [MeSH Supplementary Concept]
- BOM regimen [MeSH Supplementary Concept]
- BOMM protocol [MeSH Supplementary Concept]
- BOMP protocol [MeSH Supplementary Concept]
- CAP-M protocol [MeSH Supplementary Concept]
- CMCF protocol [MeSH Supplementary Concept]
- DMAP protocol [MeSH Supplementary Concept]
- DMV protocol [MeSH Supplementary Concept]
- F-FOMi protocol [MeSH Supplementary Concept]
- FAM II protocol [MeSH Supplementary Concept]
- FAM protocol [MeSH Supplementary Concept]
- FAM-S protocol [MeSH Supplementary Concept]
- FEM protocol [MeSH Supplementary Concept]
- FEMP protocol [MeSH Supplementary Concept]
- FILM protocol [MeSH Supplementary Concept]
- FIM protocol [MeSH Supplementary Concept]
- FLMP protocol [MeSH Supplementary Concept]
- FML protocol [MeSH Supplementary Concept]
- FMP protocol [MeSH Supplementary Concept]
- FOAM protocol [MeSH Supplementary Concept]
- FTM protocol [MeSH Supplementary Concept]
- FUDRAM protocol [MeSH Supplementary Concept]
- HMiVe protocol [MeSH Supplementary Concept]
- HexMF protocol [MeSH Supplementary Concept]
- IMAP protocol [MeSH Supplementary Concept]
- MAC-VD protocol [MeSH Supplementary Concept]
- MALF protocol [MeSH Supplementary Concept]
- MAP protocol [MeSH Supplementary Concept]
- MBCF protocol [MeSH Supplementary Concept]
- MC protocol [MeSH Supplementary Concept]
- MCM protocol [MeSH Supplementary Concept]
- MECCA protocol [MeSH Supplementary Concept]
- MEP regimen [MeSH Supplementary Concept]
- MEPH protocol [MeSH Supplementary Concept]
- MFC protocol [MeSH Supplementary Concept]
- MICE regimen [MeSH Supplementary Concept]
- MIP protocol [MeSH Supplementary Concept]
- MMC complex [MeSH Supplementary Concept]
- MMF protocol [MeSH Supplementary Concept]
- MMM protocol 1 [MeSH Supplementary Concept]
- MMM protocol 2 [MeSH Supplementary Concept]
- MPEMi protocol [MeSH Supplementary Concept]
- MQF-OK protocol [MeSH Supplementary Concept]
- MQF-OK-FT protocol [MeSH Supplementary Concept]
- MT protocol [MeSH Supplementary Concept]
- MTV protocol [MeSH Supplementary Concept]
- MV protocol 2 [MeSH Supplementary Concept]
- MVC regimen [MeSH Supplementary Concept]
- MVMF protocol [MeSH Supplementary Concept]
- MVP protocol 1 [MeSH Supplementary Concept]
- MVPF protocol [MeSH Supplementary Concept]
- MiPE protocol [MeSH Supplementary Concept]
- PEM protocol [MeSH Supplementary Concept]
- PMFV protocol [MeSH Supplementary Concept]
- PMU protocol [MeSH Supplementary Concept]
- PMUE protocol [MeSH Supplementary Concept]
- PMUE protocol 2 [MeSH Supplementary Concept]
- POMP regimen [MeSH Supplementary Concept]
- PPM protocol [MeSH Supplementary Concept]
- THP-FLPM protocol [MeSH Supplementary Concept]
- UFTM protocol [MeSH Supplementary Concept]
- VAM protocol [MeSH Supplementary Concept]
- VMM protocol [MeSH Supplementary Concept]
- desmethoxymitomycin A [MeSH Supplementary Concept]
- mallinson protocol [MeSH Supplementary Concept]
- mito-MBD protocol [MeSH Supplementary Concept]
- mitomycin C-DNA adduct [MeSH Supplementary Concept]
- mitomycin C-N(2)-deoxyguanosine adduct [MeSH Supplementary Concept]
- mitomycin C-anti-alpha-fetoprotein antibody conjugate [MeSH Supplementary Concept]
- mitomycin C-dextran [MeSH Supplementary Concept]
- mitomycin C-immunoglobulin M antibody conjugate [MeSH Supplementary Concept]
- mitozytrex [MeSH Supplementary Concept]
Related MeSH term(s)
- mitomycins [MeSH Descriptor]
See also (suggested by CISMeF)
- mitomycins [MeSH Descriptor]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Mitomycin [ICD-11 Extension code]
- Mitomycin [NCIt concept]
- Mitomycin (substance) [SNOMED CT concept]
- Product containing mitomycin (medicinal product) [SNOMED CT concept]
- mitomycin [ATC Code]
- mitomycin [SNOMED Notion]
Validated automatic mappings to BTNT
- Mitomycin A [NCIt concept]
- mitomycin [ATC Code]

Keyword's position in hierarchy(ies) :

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