alkylating agents

Preferred Label : alkylating agents;

MeSH definition : Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.;

MeSH synonym : alkylators; agents, alkylating; Alkylator; Alkylating Agent; Agent, Alkylating;

Wikipedia link : https://en.wikipedia.org/wiki/Alkylating agents;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D000477;

UMLS CUI

C0002073;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Alkylating agent (disposition) [SNOMED CT concept]
- Alkylating agents [ICD-11 Extension code]
- Alkylation Process [NCIt concept]
- alkyl groups [IUPAC Term]
- other alkylating agents [ATC Code]
CISMeF manual mappings
- Alkylating agent (substance) [SNOMED CT concept]
- Alkylating drug poisoning (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Alkylating Agent [NCIt concept]
- Product containing alkylating agent (product) [SNOMED CT concept]
- alkylating agent, nos [SNOMED Notion]
- alkylating agents [ATC Code]
Fils d'après SNOMED CT
- streptozocin [MeSH Descriptor]
Record concept(s)
- alkylating agents [MeSH concept]
SNOMED CT : is a
- mechlorethamine [MeSH Descriptor]
- mitobronitol [MeSH Descriptor]
- nitrogen mustard compounds [MeSH Descriptor]
- nitrosourea compounds [MeSH Descriptor]
- semustine [MeSH Descriptor]
See also
- mutagens [MeSH Descriptor]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- 1,2-Dimethylhydrazine [MeSH Descriptor]
- 3-(2-cyanoethyl)thymidine [MeSH Supplementary Concept]
- 5-(3-methyl-1-triazeno)imidazole-4-carboxamide [MeSH Supplementary Concept]
- EEDQ [MeSH Supplementary Concept]
- acetoxyacetylaminofluorene [MeSH Descriptor]
- amino acid chloromethyl ketones [MeSH Descriptor]
- beta-funaltrexamine [MeSH Supplementary Concept]
- chlorethylclonidine [MeSH Supplementary Concept]
- dibromoacetic acid [MeSH Supplementary Concept]
- diethyl sulfate [MeSH Supplementary Concept]
- diethylnitrosamine [MeSH Descriptor]
- dimethyl sulfate [MeSH Supplementary Concept]
- esperamicin A1 [MeSH Supplementary Concept]
- ethylnitrosourea [MeSH Descriptor]
- hepsulfam [MeSH Supplementary Concept]
- iodoacetamide [MeSH Descriptor]
- iodoacetates [MeSH Descriptor]
- isopropylmethanesulfonate [MeSH Supplementary Concept]
- methylazoxymethanol [MeSH Supplementary Concept]
- methylnitrosourea [MeSH Descriptor]
- mitomycin [MeSH Descriptor]
- monocrotaline pyrrole [MeSH Supplementary Concept]
- nitrosomethylurethane [MeSH Descriptor]
- tinidazole [MeSH Descriptor]
- tosyllysine chloromethyl ketone [MeSH Descriptor]
- tosylphenylalanyl chloromethyl ketone [MeSH Descriptor]
UMLS correspondences (same concept)
- Alkylating Agent [NCIt concept]
- Alkylating agent (substance) [SNOMED CT concept]
- Alkylating drug [ICD-11 Extension code]
- Product containing alkylating agent (product) [SNOMED CT concept]
- alkylating agent, nos [SNOMED Notion]
- alkylating agents [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients