busulfan - CISMeF

Preferred Label : busulfan;

MeSH definition : An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.;

MeSH synonym : busulphan;

CISMeF synonym : GlaxoSmithKline brand of busulfan; busulfan GlaxoSmithKline brand; busulfan orphan brand; busulfan wellcome brand; glaxo wellcome brand of busulfan; orphan brand of busulfan; wellcome brand of busulfan;

DeCS synonym : Myl ran;

MeSH hyponym : myléran; myelosan; busulfex; glyzophrol; mylecytan; myleran; busulfan wellcome; Wellcome, Busulfan;

Related MeSH term : n-Butane-1,3-di(methylsulfonate);

MeSH CAS label : 1,4-Butanediol, dimethanesulfonate;

MeSH Related Number : 55-98-1 (Busulfan);

Registry Number MeSH : 55-98-1;

Wikipedia link : https://en.wikipedia.org/wiki/Busulfan;

Codes EINECS : 200-250-2;

Is substance : O;

UNII : G1LN9045DK;

InChIKey : COVZYZSDYWQREU-UHFFFAOYSA-N;

Details

Origin ID

D002066;

UMLS CUI

C0006463;

ATC code(s)
- busulfan [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Busulfan [LOINC Challenge]
- Myleran [ICHI extension code]
CISMeF manual mappings
- Busulfan [ICD-11 Extension code]
- busulfan [Substance BNPC]
Currated CISMeF NLP mapping
- Busulfan [LOINC component]
- Busulfan [NCIt concept]
- Busulfan (substance) [SNOMED CT concept]
- busulfan [SNOMED Notion]
Pharmacological action(s)
- antineoplastic agents, alkylating [MeSH Descriptor]
- myeloablative agonists [MeSH Descriptor]
Record concept(s)
- busulfan [MeSH concept]
- busulfan wellcome [MeSH concept]
- busulfex [MeSH concept]
- glyzophrol [MeSH concept]
- myelosan [MeSH concept]
- mylecytan [MeSH concept]
- myleran [MeSH concept]
- n-Butane-1,3-di(methylsulfonate) [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,4-butanediol diisethionate [MeSH Supplementary Concept]
- 4-methanesulfonyloxybutanol [MeSH Supplementary Concept]
- BUCY-2 protocol [MeSH Supplementary Concept]
- BuCEt protocol [MeSH Supplementary Concept]
- dimethylmyleran [MeSH Supplementary Concept]
- treosulfan [MeSH Supplementary Concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Busulfan [ICD-11 Extension code]
- Busulfan [LOINC Challenge]
- Busulfan [NCIt concept]
- Busulfan [LOINC component]
- Busulfan (substance) [SNOMED CT concept]
- Product containing busulfan (medicinal product) [SNOMED CT concept]
- busulfan [ATC Code]
- busulfan [Substance BNPC]
- busulfan [SNOMED Notion]
Validated automatic mappings to BTNT
- busulfan [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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