topotecan - CISMeF

Preferred Label : topotecan;

MeSH definition : An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.;

MeSH synonym : 9 dimethylaminomethyl 10 hydroxycamptothecin; 9-dimethylaminomethyl-10-hydroxycamptothecin;

CISMeF synonym : SmithKline beecham brand of topotecan hydrochloride; hycamtamine;

DeCS synonym : Hycamtamine;

MeSH hyponym : NSC-609699; hycamtin; topotecan hydrochloride; SK&F-104864-A; Hydrochloride, Topotecan; Nogitecan Hydrochloride; Hydrochloride, Nogitecan; Topotecan Monohydrochloride, (S)-Isomer; SK&F 104864 A; SK&F104864A; SKF-104864-A; SKF 104864 A; SKF104864A; NSC 609699; NSC609699;

MeSH Related Number : topotecan hydrochloride; 119413-54-6 (Topotecan hydrochloride); 123948-87-8 (Topotecan); 956S425ZCY;

Registry Number MeSH : 123948-87-8;

Related CAS MeSH : 956S425ZCY (Topotecan hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Topotecan;

Is substance : O;

UNII : 7M7YKX2N15;

InChIKey : UCFGDBYHRUNTLO-QHCPKHFHSA-N;

Details

Origin ID

D019772;

UMLS CUI

C0146224;

ATC code(s)
- topotecan [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Oral Topotecan Hydrochloride [NCIt concept]
- Toksook [NCIt concept]
- Topotecan [ICD-11 Extension code]
- Topotecan Hydrochloride [NCIt concept]
- Topotecan chlorohydrate (substance) [Inactive SNOMED CT concept]
- Topotecan hydrochloride (substance) [SNOMED CT concept]
- topotecan [ATC Code]
- topotecan chlorohydrate [SNOMED Notion]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
- topoisomerase I inhibitors [MeSH Descriptor]
Record concept(s)
- Hycamtamine [MeSH concept]
- NSC-609699 [MeSH concept]
- SK&F-104864-A [MeSH concept]
- hycamtin [MeSH concept]
- topotecan [MeSH concept]
- topotecan hydrochloride [MeSH concept]
Related MeSH Supplementary Concept(s)
- CAT combination [MeSH Supplementary Concept]
- CAT-G protocol [MeSH Supplementary Concept]
- CPT protocol [MeSH Supplementary Concept]
- N-desmethyltopotecan [MeSH Supplementary Concept]
- T 0128 [MeSH Supplementary Concept]
- T 2153 [MeSH Supplementary Concept]
- TA protocol [MeSH Supplementary Concept]
- TAM protocol [MeSH Supplementary Concept]
- TMC regimen [MeSH Supplementary Concept]
- TVTG protocol [MeSH Supplementary Concept]
- topotecan-20-O-(4-fluorophenoxyacetate) [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients