amino acid chloromethyl ketones

Preferred Label : amino acid chloromethyl ketones;

MeSH definition : Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.;

MeSH synonym : chloromethyl ketones, peptide; ketones, peptide chloromethyl; peptide chloromethyl ketones;

MeSH annotation : serine proteinase inhib; DF: AACK;

Is substance : O;

Details

Origin ID

D000590;

UMLS CUI

C0002512;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- alkylating agents [MeSH Descriptor]
- protein synthesis inhibitors [MeSH Descriptor]
- serine proteinase inhibitors [MeSH Descriptor]
Record concept(s)
- amino acid chloromethyl ketones [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-oxodecyl-arginyl-valyl-lysyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- 2,4-di-Cl-Cbz-Val-Asp-fmk [MeSH Supplementary Concept]
- 5(6)-carboxyfluoresceinylleucyl chloromethyl ketone [MeSH Supplementary Concept]
- 5(6)-carboxyfluoresceinylphenylalanyl chloromethyl ketone [MeSH Supplementary Concept]
- 5-iodo-2-methoxybenzylcarbonyl-valyl-aspartic acid fluoromethyl ketone [MeSH Supplementary Concept]
- 7-amino-3-benzyloxycarbonylamino-1-chloroheptan-2-one [MeSH Supplementary Concept]
- BFCCCMK [MeSH Supplementary Concept]
- N(alpha)-((acetylthio)acetyl)-phenylalanyl-prolyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- N(alpha)-2,4-dinitrophenyllysine chloromethyl ketone [MeSH Supplementary Concept]
- N-(benzyloxycarbonyl)-alanyl-glycyl-phenylalanyl chloromethyl ketone [MeSH Supplementary Concept]
- N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone [MeSH Supplementary Concept]
- N-acetylalanyl-alanyl-alanine chloromethyl ketone [MeSH Supplementary Concept]
- N-acetylalanyl-alanyl-prolyl-alanine chloromethyl ketone [MeSH Supplementary Concept]
- N-alpha-carbobenzoxypyroglutamic acid chloromethyl ketone [MeSH Supplementary Concept]
- N-benzyloxycarbonylglycyl-leucyl-phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- N-formylnorleucyl-leucyl-phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- N-methylphenylalanyl-prolyl-arginine 1,1-difluorobutyl ketone [MeSH Supplementary Concept]
- N-tert-butyloxycarbonyl-aspartyl (benzyl)chloromethylketone [MeSH Supplementary Concept]
- O-methylsuccinyl-alanyl-alanyl-valyl-chloromethyl ketone [MeSH Supplementary Concept]
- RH 4032 [MeSH Supplementary Concept]
- Z-Ala-Ala-Asp-chloromethylketone [MeSH Supplementary Concept]
- Z-Asp-2,6-dichlorobenzoyl-oxymethylketone [MeSH Supplementary Concept]
- ZPCK [MeSH Supplementary Concept]
- acetyl-aspartyl-glutamyl-valyl-aspartyl-chloromethyl ketone [MeSH Supplementary Concept]
- acetyl-aspartyl-glutamyl-valyl-lysine chloromethyl ketone [MeSH Supplementary Concept]
- acetyl-aspartyl-valyl-alanyl-aspartyl fluoromethyl ketone [MeSH Supplementary Concept]
- acetylleucine chloromethyl ketone [MeSH Supplementary Concept]
- acetylphenyl-alanyl-lysine chloromethyl ketone [MeSH Supplementary Concept]
- alanine chloromethyl ketone [MeSH Supplementary Concept]
- alanyl-alanyl-phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- alanyl-alanyl-tyrosyl(benzyl)-chloromethylketone [MeSH Supplementary Concept]
- alanyl-prolyl-phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- alpha(N)-(4-nitrobenzyloxycarbonylarginine chloromethyl ketone) [MeSH Supplementary Concept]
- arginine chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonyl-alanyl-alanyl--prolyl-phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonyl-arginyl-(O-benzyl)serine chloromethylketone [MeSH Supplementary Concept]
- benzyloxycarbonyl-valyl-alanyl-(methyl)aspartic acid fluoromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonyl-valyl-aspartic acid fluoromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonylalanine chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonylalanyl-alanine chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonylalanyl-alanyl phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonylglycylglycylphenylalanylchloromethane [MeSH Supplementary Concept]
- benzyloxycarbonylphenylalanyl-alanine chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonyltryptophanylchloromethane [MeSH Supplementary Concept]
- benzyloxycarbonyltyrosyl-alanyl-valyl-aspartyl chloromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone [MeSH Supplementary Concept]
- benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone [MeSH Supplementary Concept]
- biotinyldicaproyl-glutamyl-glycyl-arginyl-chloromethylketone [MeSH Supplementary Concept]
- biotinyldicaproyl-phenylalanyl-prolyl-arginyl-chloromethylketone [MeSH Supplementary Concept]
- bradykinin chloromethyl ketone [MeSH Supplementary Concept]
- butyloxycarbonyl-O-methyl-aspartyl-fluoromethyl ketone [MeSH Supplementary Concept]
- butyloxycarbonyl-aspartyl-fluoromethyl ketone [MeSH Supplementary Concept]
- carbobenzyloxy-valyl-asparaginyl-seryl-threonyl-leuyl-glutamine chloromethylketone [MeSH Supplementary Concept]
- carbobenzyloxyleucyl-tyrosine chloromethyl ketone [MeSH Supplementary Concept]
- dansyl-glutamyl-glycyl-arginyl chloromethyl ketone-treated factor xa [MeSH Supplementary Concept]
- dansylalanyllysine chloromethyl ketone [MeSH Supplementary Concept]
- dansylglutamyl-glycyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- dansylglutamyl-glycyl-arginyl chloromethyl ester [MeSH Supplementary Concept]
- decanoylRVKRchloromethylketone [MeSH Supplementary Concept]
- enkephalin, N-(1-(Cl-Ac)-3-methylbutyl)-PheNH2(4)- [MeSH Supplementary Concept]
- gamma-glutamylalanine chloromethyl ketone [MeSH Supplementary Concept]
- glutamyl-glycyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- glutamyl-glycyl-arginyl chloromethyl ketone inactivated human factor xa [MeSH Supplementary Concept]
- glutamyl-glycyl-arginyl-chloromethyl ketone [MeSH Supplementary Concept]
- iodotyrosyl-prolyl-arginyl chloromethyl ketone [MeSH Supplementary Concept]
- isoleucyl-glutamyl-glycyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- isoleucyl-phenylalanyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- isoleucyl-phenylalanyl-lysine chloromethyl ketone [MeSH Supplementary Concept]
- leucine chloromethyl ketone [MeSH Supplementary Concept]
- lysine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinate-alanyl-alanyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-Ala-Ala-Pro-Phe-chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-alanyl-prolyl-leucine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-alanyl-prolyl-phenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-alanyl-prolyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-prolyl-alanine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- nalpha-acetyllysine chloromethyl ketone [MeSH Supplementary Concept]
- phenylalanyl-alanyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- phenylalanyl-alanyl-lysine chloromethyl ketone [MeSH Supplementary Concept]
- phenylalanyl-phenylalanyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- phenylalanyl-prolyl-arginine chloromethyl ketone-thrombin [MeSH Supplementary Concept]
- phenylalanyl-prolyl-arginine-chloromethyl ketone [MeSH Supplementary Concept]
- phenylalanylarginine fluoromethyl ketone [MeSH Supplementary Concept]
- proline chloromethyl ketone [MeSH Supplementary Concept]
- prolyl-phenylalanyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- pyroglutamic acid chloromethyl ketone [MeSH Supplementary Concept]
- quinoline-val-asp(OMe)-CH2-OPH [MeSH Supplementary Concept]
- succinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- succinyl-alanylalanyl-prolyl-phenylalanine chloromethylketone [MeSH Supplementary Concept]
- tosylglycine chloromethyl ketone [MeSH Supplementary Concept]
- trypsin-1-chloro-3-(carbobenzyloxyamino)-7-aminoheptan-2-one complex [MeSH Supplementary Concept]
- tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone [MeSH Supplementary Concept]
- tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone [MeSH Supplementary Concept]
- tyrosyl-alanyl-lysyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- tyrosyl-prolyl-arginyl chloromethyl ketone [MeSH Supplementary Concept]
- valyl-phenylalanyl-lysine chloromethyl ketone [MeSH Supplementary Concept]
- valylphenylalanyl-lysylchloromethane [MeSH Supplementary Concept]
- z-Val-Ala-Asp(Ome)-fluoromethylketone [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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