tosyllysine chloromethyl ketone

Preferred Label : tosyllysine chloromethyl ketone;

MeSH definition : An inhibitor of SERINE ENDOPEPTIDASES. Acts as an alkylating agent and is known to interfere with the translation process.;

MeSH synonym : tosyllysyl chloromethane; ketone, tosyllysine chloromethyl; chloromethane, tosyllysyl; chloromethyl ketone, tosyllysine; tlck; chlorotosylamidoaminoheptanone;

MeSH CAS label : benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-;

Registry Number MeSH : 2104-86-1;

Is substance : O;

Details

Origin ID

D014107;

UMLS CUI

C0040495;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- alkylating agents [MeSH Descriptor]
- protein synthesis inhibitors [MeSH Descriptor]
- serine proteinase inhibitors [MeSH Descriptor]
Record concept(s)
- tosyllysine chloromethyl ketone [MeSH concept]
Related MeSH Supplementary Concept(s)
- tosyllysine chloromethyl ketone-thrombin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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