Mitomycin Antineoplastic Antibiotic

Preferred Label : Mitomycin Antineoplastic Antibiotic;

NCIt synonyms : Mitomycin Antibiotic;

NCIt related terms : mitomycin;

NCIt definition : Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and dione moieties. Bioreductively activated mitomycin antibiotics generate oxygen radicals and alkylate DNA, forming inter-strand cross-links and inhibiting DNA synthesis.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antitumor antibiotics.;

ChEBI ID : CHEBI:25357;

Codes from synonyms : CDR0000045538;

Details

Origin ID

C663;

UMLS CUI

C0026254;

Automatic exact mappings (from CISMeF team)
- Mitomycin [ICHI extension code]
- Mitomycin [SMS substance]
- Product containing mitomycin (medicinal product) [SNOMED CT concept]
- mitomycin [MeSH Descriptor]
- mitomycin [MeSH concept]
- mitomycin [ATC Code]
- mitomycin [SNOMED Notion]
- mitomycin A [MeSH Supplementary Concept]
- mitomycin A [MeSH concept]
Currated CISMeF NLP mapping
- mitomycins [MeSH Descriptor]
- mitomycins [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- mitomycins [MeSH concept]
- mitomycins [MeSH Descriptor]
Validated automatic mappings to BTNT
- Mitomycin [ICD-11 Extension code]
- Mitomycin (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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