plicamycin - CISMeF

Preferred Label : plicamycin;

MeSH definition : A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.;

MeSH synonym : aureolic acid; mitramycin; Mithramycin;

CISMeF synonym : acid, aureolic;

MeSH CAS label : mithramycin;

MeSH Related Number : 18378-89-7 (Plicamycin);

Registry Number MeSH : 18378-89-7;

Wikipedia link : https://en.wikipedia.org/wiki/Plicamycin;

Is substance : O;

UNII : NIJ123W41V;

InChIKey : CFCUWKMKBJTWLW-BKHRDMLASA-N;

Details

Origin ID

D008926;

UMLS CUI

C0026234;

ATC code(s)
- plicamycin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Plicamycin poisoning (disorder) [SNOMED CT concept]
Indexing information
- mtrX protein, streptomyces argillaceus [MeSH Supplementary Concept]
- mtrY protein, streptomyces argillaceus [MeSH Supplementary Concept]
Pharmacological action(s)
- Calcium-Regulating Hormones and Agents [MeSH Descriptor]
- antibiotics, antineoplastic [MeSH Descriptor]
- fluorescent dyes [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
- protein synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- plicamycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- SDK compound [MeSH Supplementary Concept]
- UCH 9 [MeSH Supplementary Concept]
- bis(mithromycin)iron(II) [MeSH Supplementary Concept]
- chromomycin A2 [MeSH Supplementary Concept]
- demycarosyl-3D-digitoxosylmithramycin SK [MeSH Supplementary Concept]
- durhamycin A [MeSH Supplementary Concept]
- durhamycin B [MeSH Supplementary Concept]
- mithramycin A [MeSH Supplementary Concept]
- mithramycin SK [MeSH Supplementary Concept]
- premithramycinone G [MeSH Supplementary Concept]
- variamycin [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing plicamycin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Mithramycin [ICD-11 Extension code]
- Plicamycin [ICD-11 Extension code]
- Plicamycin [NCIt concept]
- Plicamycin (substance) [SNOMED CT concept]
- Product containing plicamycin (medicinal product) [SNOMED CT concept]
- plicamycin [ATC Code]
- plicamycin [SNOMED Notion]
Validated automatic mappings to BTNT
- plicamycin [ATC Code]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients