nogalamycin - CISMeF

Preferred Label : nogalamycin;

MeSH definition : An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.;

MeSH hyponym : U-15167; U 15167; U15167;

MeSH CAS label : 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid, 11-((6-deoxy-3-C-methyl-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-4-(dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6,13-dimethyl-9,16-dioxo-, methyl ester, (2R-(2alpha,3beta,4alpha,5beta,6alpha,11beta,13alpha,14alpha))-;

MeSH Related Number : 1404-15-5 (Nogalamycin);

Registry Number MeSH : 1404-15-5;

Is substance : O;

UNII : L059DCD6IP;

InChIKey : KGTDRFCXGRULNK-JYOBTZKQSA-N;

Details

Origin ID

D009621;

UMLS CUI

C0028261;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Nogalamycin [SMS substance]
- Nogalamycin [NCIt concept]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- intercalating agents [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- U-15167 [MeSH concept]
- nogalamycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- disnogalamycin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Nogalamycin [NCIt concept]

Keyword's position in hierarchy(ies) :

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