intercalating agents

Preferred Label : intercalating agents;

MeSH definition : Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.;

MeSH synonym : compounds, intercalative; ligands, intercalating; intercalating ligands; agents, intercalating; intercalators; intercalative compounds; Intercalative Compound; Compound, Intercalative; Intercalating Agent; Agent, Intercalating; Intercalator; Intercalating Ligand; Ligand, Intercalating;

MeSH annotation : agents capable of inserting themselves ... between the successive bases in DNA; used in DNA studies; D25-26 qualif;

Wikipedia link : https://en.wikipedia.org/wiki/Intercalating agent;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D007364;

UMLS CUI

C0021717;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- intercalation [IUPAC Term]
Currated CISMeF NLP mapping
- DNA Intercalating Agent [NCIt concept]
Indexing information
- (2-(1-(3-methoxycarbonylmethyl-1H-indol-2-yl)-1-methylethyl)-1H-indol-3-yl)acetic acid methyl ester [MeSH Supplementary Concept]
- (dipyrido(3,2-a:2',3'-c)phenazine)(glycinato)copper(II) [MeSH Supplementary Concept]
- 1-pyrenebutylamine [MeSH Supplementary Concept]
- 9-methoxy-6-(piperazin-1-yl)-11H-indeno(1,2-c)quinoline-11-one O-3-(dimethylamino)propyl oxime [MeSH Supplementary Concept]
- PtCl(tmen))(2)(HNC(13)H(7)(NHCH(2)CH(2))2 [MeSH Supplementary Concept]
- aminoplatin [MeSH Supplementary Concept]
- bis(bis(N-allylbenzimidazol-2-ylmethyl)benzylamine)silver(I) [MeSH Supplementary Concept]
- pentaamineruthenium-(3-(2-phenanthren-9-ylvinyl)pyridine) [MeSH Supplementary Concept]
Record concept(s)
- intercalating agents [MeSH concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
Substance(s)
- 1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidene)quinolinium [MeSH Supplementary Concept]
- 1,1'-(4,4,7,7-tetramethyl-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-thiazole)-2-methylidene)quinolinium [MeSH Supplementary Concept]
- 1,10-phenanthroline [MeSH Supplementary Concept]
- 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline [MeSH Supplementary Concept]
- 9-amino-6-chloro-2-methoxyacridine [MeSH Supplementary Concept]
- DAPI [MeSH Supplementary Concept]
- NSC 366140 [MeSH Supplementary Concept]
- acriflavine [MeSH Descriptor]
- ametantrone [MeSH Supplementary Concept]
- amonafide [MeSH Supplementary Concept]
- amsacrine [MeSH Descriptor]
- angelicin [MeSH Supplementary Concept]
- diminazene aceturate [MeSH Supplementary Concept]
- ditercalinium [MeSH Supplementary Concept]
- elliptinium [MeSH Supplementary Concept]
- ethidium homodimer [MeSH Supplementary Concept]
- ferroin [MeSH Supplementary Concept]
- gilvocarcin V [MeSH Supplementary Concept]
- mitonafide [MeSH Supplementary Concept]
- nogalamycin [MeSH Descriptor]
- propidium [MeSH Descriptor]
UMLS correspondences (same concept)
- DNA Intercalating Agent [NCIt concept]

Keyword's position in hierarchy(ies) :

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