fusaric acid - CISMeF

Preferred Label : fusaric acid;

MeSH definition : A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.;

MeSH synonym : acid, fusaric; 5-butyl-2-pyridinedicarboxylic acid; 5 butyl 2 pyridinedicarboxylic acid; acid, 5-butyl-2-pyridinedicarboxylic;

CISMeF synonym : 5-butylpyridine-3-carboxylic acid;

MeSH hyponym : calcium fusarate; Fusarate, Calcium;

MeSH CAS label : 2-Pyridinecarboxylic acid, 5-butyl-;

MeSH Related Number : 536-69-6 (Fusaric acid);

Registry Number MeSH : 536-69-6;

MeSH annotation : /biosyn permitted if by organism;

Codes EINECS : 208-643-0;

Is substance : O;

UNII : JWJ963070N;

InChIKey : DGMPVYSXXIOGJY-UHFFFAOYSA-N;

Details

Origin ID

D005669;

UMLS CUI

C0016869;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- 5-butylpyridine-3-carboxylic acid [Substance BNPC]
Pharmacological action(s)
- dopamine agents [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- calcium fusarate [MeSH concept]
- fusaric acid [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5-(3',4'-dihydroxybutyl)-2-pyridinecarboxylic acid [MeSH Supplementary Concept]
- 5-(3'-carboxypropyl)-2-pyridinecarboxylic acid [MeSH Supplementary Concept]
- 5-(4'-chlorobutyl)picolinic acid [MeSH Supplementary Concept]
- 9,10-dehydrofusaric acid [MeSH Supplementary Concept]
- bupicomide [MeSH Supplementary Concept]
- fusaric acid N,N-diethylaminoethylamide [MeSH Supplementary Concept]
- fusarinolic acid [MeSH Supplementary Concept]
- methyl fusarate [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 5-butylpyridine-3-carboxylic acid [Substance BNPC]

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