lobucavir - CISMeF

Preferred Label : lobucavir;

MeSH note : structure given in first source; inhibits the replication of HIV virus in T cells, monocytes & macrophages in vitro by inhibiting DNA polymerase and viral DNA synthesis;

CISMeF synonym : BMS 180194; SQ 33054; SQ 34514;

MeSH synonym : 9-(2,3-bis-(hydroxymethyl)-1-cyclobutyl)guanine; carbocyclic oxetanocin G; cyclobut-G; C-OXT-G; 2-amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-6H-purin-6-one;

MeSH hyponym : SQ-33054; SQ-34,514; BMS-180194;

MeSH Related Number : 126062-18-8;

Registry Number MeSH : 126062-18-8;

Is substance : O;

UNII : 8U5PYQ1R2E;

InChIKey : GWFOVSGRNGAGDL-FSDSQADBSA-N;

Details

Origin ID

C063638;

UMLS CUI

C0286536;

Currated CISMeF NLP mapping
- Lobucavir [NCIt concept]
MeSH indexing information
- DNA-Directed DNA polymerase [MeSH Descriptor]
- reverse transcriptase inhibitors [MeSH Descriptor]
MeSH term(s) associated for indexing
- guanine [MeSH Descriptor]
Pharmacological action(s)
- anti-hiv agents [MeSH Descriptor]
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- BMS 180194 [MeSH concept]
- SQ 33054 [MeSH concept]
- SQ 34514 [MeSH concept]
- lobucavir [MeSH concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lobucavir [NCIt concept]

Keyword's position in hierarchy(ies) :

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