DNA-Directed DNA polymerase

Preferred Label : DNA-Directed DNA polymerase;

MeSH definition : DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.;

MeSH synonym : dna polymerases; polymerases, dna; dna-dependent dna polymerases; polymerases, dna-dependent dna; dna polymerase, dna-directed; polymerase, dna-directed dna; dna dependent dna polymerases; dna polymerases, dna-dependent; DNA directed DNA polymerase; DNA Polymerase; Polymerase, DNA;

MeSH hyponym : DNA polymerase N3; Polymerase N3, DNA;

MeSH CAS label : Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed);

MeSH Related Number : 9012-90-2 (CAS RN);

Registry Number MeSH : EC 2.7.7.7;

MeSH annotation : general; prefer specifics;

Is substance : O;

UNII : EC 2.7.7.7;

Details

Origin ID

D004259;

UMLS CUI

C0012892;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- DNA-directed DNA Polymerase [NCIt concept]
- Deoxyribonucleic acid-directed deoxyribonucleic acid polymerase (substance) [SNOMED CT concept]
- dna-directed dna polymerase [SNOMED Notion]
Indexing information
- 1-O-(6'-sulfo-alpha-D-glucopyranosyl)-2,3-di-O-phytanyl-sn-glycerol [MeSH Supplementary Concept]
- 1-beta-arabinofuranosyl-5-butyluracil-5'-triphosphate [MeSH Supplementary Concept]
- 1-beta-arabinofuranosyl-5-ethyluracil 5'-triphosphate [MeSH Supplementary Concept]
- 1-beta-arabinofuranosyl-5-propyluracil-5'-triphosphate [MeSH Supplementary Concept]
- 1-deoxyrubralactone [MeSH Supplementary Concept]
- 2-hexaprenylhydroquinone [MeSH Supplementary Concept]
- 3,4-di-O-galloyl-5-O-digalloylquinic acid [MeSH Supplementary Concept]
- 4-n-butylanilino dATP [MeSH Supplementary Concept]
- 5-((1-(2-bromobenzoyl)-5-chloro-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione [MeSH Supplementary Concept]
- DNA polymerase stimulatory protein, Epstein-Barr virus [MeSH Supplementary Concept]
- DNA polymerase-modifying protein, tetrahymena thermophila [MeSH Supplementary Concept]
- G(8-5m)T [MeSH Supplementary Concept]
- ITBA-16 [MeSH Supplementary Concept]
- N(2)-(4-n-butylphenyl)-2'--deoxyguanosine 5'-imidotriphosphate [MeSH Supplementary Concept]
- T7C-45 protein, bacteriophage T4 [MeSH Supplementary Concept]
- T7C-45 protein-ANBD [MeSH Supplementary Concept]
- carbonyldiphosphonate [MeSH Supplementary Concept]
- cdc6 protein, S pombe [MeSH Supplementary Concept]
- digallic acid [MeSH Supplementary Concept]
- ganciclovir triphosphate [MeSH Supplementary Concept]
- gene 43 protein, enterobacteria phage T4 [MeSH Supplementary Concept]
- gene 44 protein, enterobacteria phage T4 [MeSH Supplementary Concept]
- gene 45 protein, enterobacteria phage T4 [MeSH Supplementary Concept]
- gp62 protein, bacteriophage T4 [MeSH Supplementary Concept]
- lobucavir [MeSH Supplementary Concept]
- lucidenic acid O [MeSH Supplementary Concept]
- lucidenic lactone [MeSH Supplementary Concept]
- penciclovir triphosphate [MeSH Supplementary Concept]
- polycitone A [MeSH Supplementary Concept]
- sch 725680 [MeSH Supplementary Concept]
- sculezonone A [MeSH Supplementary Concept]
- sculezonone B [MeSH Supplementary Concept]
- sulfoquinovosyl diglyceride [MeSH Supplementary Concept]
Record concept(s)
- DNA polymerase N3 [MeSH concept]
- DNA-Directed DNA polymerase [MeSH concept]
Related MeSH Supplementary Concept(s)
- AtREV3 protein, arabidopsis [MeSH Supplementary Concept]
- BALF5 protein, epstein-barr virus [MeSH Supplementary Concept]
- DNA polymerase CI, triticum aestivum [MeSH Supplementary Concept]
- DNA polymerase V, E coli [MeSH Supplementary Concept]
- DNA polymerase X [MeSH Supplementary Concept]
- DNA polymerase lambda, arabidopsis [MeSH Supplementary Concept]
- DNA polymerase mu [MeSH Supplementary Concept]
- DNA polymerase tfu [MeSH Supplementary Concept]
- DNA polymerase zeta [MeSH Supplementary Concept]
- DNA polymerase, simplexvirus [MeSH Supplementary Concept]
- DNA polymerase, thermus thermophilus [MeSH Supplementary Concept]
- DNA polymerase, vaccinia virus [MeSH Supplementary Concept]
- DNA replicase [MeSH Supplementary Concept]
- DNA synthesome [MeSH Supplementary Concept]
- DNApol-theta protein, Drosophila [MeSH Supplementary Concept]
- DyNAzyme polymerase [MeSH Supplementary Concept]
- PAP2 protein, S cerevisiae [MeSH Supplementary Concept]
- POL4 protein, S pombe [MeSH Supplementary Concept]
- POL5 protein, S cerevisiae [MeSH Supplementary Concept]
- POLG protein, human [MeSH Supplementary Concept]
- POLG2 protein, human [MeSH Supplementary Concept]
- POLH-1 protein, C elegans [MeSH Supplementary Concept]
- POLK protein, arabidopsis [MeSH Supplementary Concept]
- POLK protein, human [MeSH Supplementary Concept]
- POLK-1 protein, C elegans [MeSH Supplementary Concept]
- POLN protein, human [MeSH Supplementary Concept]
- POLN protein, zebrafish [MeSH Supplementary Concept]
- Pol32 protein, S cerevisiae [MeSH Supplementary Concept]
- PolB P1 protein, agrocybe aegerita [MeSH Supplementary Concept]
- PolB protein, agrocybe aegerita [MeSH Supplementary Concept]
- PolC protein, bacteria [MeSH Supplementary Concept]
- PolD DNA polymerase, pyrococcus horikoshii [MeSH Supplementary Concept]
- PolIA protein, Arabidopsis [MeSH Supplementary Concept]
- PolIB protein, Arabidopsis [MeSH Supplementary Concept]
- Polg-1 protein, C elegans [MeSH Supplementary Concept]
- Polm protein, mouse [MeSH Supplementary Concept]
- PrimPol protein, human [MeSH Supplementary Concept]
- Primpol protein, mouse [MeSH Supplementary Concept]
- RC-1 recombination protein complex [MeSH Supplementary Concept]
- REV1 protein, human [MeSH Supplementary Concept]
- REV3 protein, S cerevisiae [MeSH Supplementary Concept]
- REV3L protein, human [MeSH Supplementary Concept]
- REV3L protein, mouse [MeSH Supplementary Concept]
- REV7 protein, S cerevisiae [MeSH Supplementary Concept]
- REV7 protein, arabidopsis [MeSH Supplementary Concept]
- Rad30 protein [MeSH Supplementary Concept]
- Rev1 protein, mouse [MeSH Supplementary Concept]
- Rev3 protein, mouse [MeSH Supplementary Concept]
- TEBICHI protein, arabidopsis [MeSH Supplementary Concept]
- TENT4A protein, human [MeSH Supplementary Concept]
- UL54 protein, human herpesvirus 5 [MeSH Supplementary Concept]
- UlTma DNA polymerase [MeSH Supplementary Concept]
- UmuC protein, E coli [MeSH Supplementary Concept]
- UmuD protein, E coli [MeSH Supplementary Concept]
- bacteriophage RB69 DNA polymerase [MeSH Supplementary Concept]
- bacteriophage T7 induced DNA polymerase [MeSH Supplementary Concept]
- dbh protein, sulfolobus solfataricus [MeSH Supplementary Concept]
- deep vent DNA polymerase [MeSH Supplementary Concept]
- dnaN protein, bacteria [MeSH Supplementary Concept]
- gene 43 protein, enterobacteria phage T4 [MeSH Supplementary Concept]
- pfu DNA polymerase [MeSH Supplementary Concept]
- polV(R391) protein, E coli [MeSH Supplementary Concept]
- polg protein, mouse [MeSH Supplementary Concept]
- polk protein, mouse [MeSH Supplementary Concept]
- polk protein, rat [MeSH Supplementary Concept]
- polk protein, xenopus [MeSH Supplementary Concept]
- poly(A).oligo(dT)-dependent DNA polymerase [MeSH Supplementary Concept]
- pwo polymerase [MeSH Supplementary Concept]
- pyrococcus sp GB-D DNA polymerase [MeSH Supplementary Concept]
- pyrostase polymerase [MeSH Supplementary Concept]
- tet DNA polymerase [MeSH Supplementary Concept]
- thy Pol-2 intein [MeSH Supplementary Concept]
- tli polymerase [MeSH Supplementary Concept]
- tth polymerase [MeSH Supplementary Concept]
Related MeSH term(s)
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DNA Polymerase [NCIt concept]
- DNA-directed DNA Polymerase [NCIt concept]
- Deoxyribonucleic acid-directed deoxyribonucleic acid polymerase (substance) [SNOMED CT concept]
- dna-directed dna polymerase [SNOMED Notion]
- polymerase DNA [LOINC part]

Keyword's position in hierarchy(ies) :

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