dichlororibofuranosylbenzimidazole

Preferred Label : dichlororibofuranosylbenzimidazole;

MeSH definition : An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation.;

MeSH synonym : dichlorobenzimidazole riboside; drb; 5,6 dichloro 1 beta ribofuranosylbenzimidazole; 5,6-dichloro-1-beta-d-ribofuranosyl-1-h-benzimidazol; riboside, dichlorobenzimidazole; 5,6 dichloro 1 beta d ribofuranosyl 1 h benzimidazol; 5,6-dichloro-1-beta-ribofuranosylbenzimidazole;

MeSH CAS label : 1H-Benzimidazole, 5,6-dichloro-1-beta-D-ribofuranosyl-;

Registry Number MeSH : 53-85-0;

MeSH annotation : DF: DCRFB;

Wikipedia link : https://en.wikipedia.org/wiki/Dichlororibofuranosylbenzimidazole;

Is substance : O;

Details

Origin ID

D004004;

UMLS CUI

C0012084;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- nucleic acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- dichlororibofuranosylbenzimidazole [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate [MeSH Supplementary Concept]
- maribavir [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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