Protease Inhibitor

Preferred Label : Protease Inhibitor;

NCIt synonyms : Protease Inhibitors;

NCIt definition : Any substance that inhibits a protease, an enzyme that breaks peptide bonds. Proteases are required for many cell processes and inhibition of proteases can inhibit viral replication, inflammatory responses, proliferation, and tumor growth.;

Alternative definition : NCI-GLOSS: A compound that interferes with the ability of certain enzymes to break down proteins. Some protease inhibitors can keep a virus from making copies of itself (for example, AIDS virus protease inhibitors), and some can prevent cancer cells from spreading.;

ChEBI ID : CHEBI:37670;

Codes from synonyms : CDR0000045977;

Details

Origin ID

C783;

UMLS CUI

C0033607;

Automatic exact mappings (from CISMeF team)
- Protease inhibitor (disposition) [SNOMED CT concept]
- Protease inhibitors [ICD-11 Extension code]
- Substance with protease inhibitor mechanism of action (substance) [SNOMED CT concept]
- protease inhibitor [COVID-19 Thesaurus concept]
Currated CISMeF NLP mapping
- Substance with peptide hydrolase inhibitor mechanism of action (substance) [SNOMED CT concept]
- protease inhibitors [ATC Code]
- protease inhibitors [MeSH Descriptor]
- protease inhibitors [MeSH concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing peptide hydrolase inhibitor (product) [SNOMED CT concept]
- Substance with peptide hydrolase inhibitor mechanism of action (substance) [SNOMED CT concept]
- protease inhibitors [MeSH concept]
- protease inhibitors [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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