Preferred Label : saquinavir;
MeSH definition : An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site.
It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits
CYTOCHROME P-450 CYP3A.;
MeSH synonym : saquinivir;
CISMeF synonym : 149845-06-7 (Saquinavir monomethanesulfonate);
MeSH hyponym : Saquinavir Monomethanesulfonate; invirase; ro 31-8959; Ro 31 8959; Ro 318959; Monomethanesulfonate, Saquinavir; Saquinavir Mesylate;
MeSH Related Number : saquinavir monomethanesulfonate; 127779-20-8 (Saquinavir); 149845-06-7 (monomethanesulfonate (salt)); UHB9Z3841A;
Registry Number MeSH : 127779-20-8;
Related CAS MeSH : UHB9Z3841A (Saquinavir monomethanesulfonate);
Wikipedia link : https://en.wikipedia.org/wiki/Saquinavir;
Is substance : O;
UNII : L3JE09KZ2F;
InChIKey : QWAXKHKRTORLEM-UGJKXSETSA-N;
Origin ID : D019258;
UMLS CUI : C0286738;
ATC code(s)
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Manual BTNT mappings - CISMeF
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site.
It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits
CYTOCHROME P-450 CYP3A.
https://www.ema.europa.eu/medicines/human/EPAR/Invirase
2012
United Kingdom
English
French
syndication feed
saquinavir
treatment outcome
hiv protease inhibitors
hiv protease inhibitors
adult
hiv infections
saquinavir
saquinavir
drug evaluation
summary of product characteristics
package leaflet
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http://www.has-sante.fr/portail/jcms/c_1046814/invirase
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-04/invirase_-_ct-8732.pdf
2011
France
French
saquinavir
administration, oral
insurance, health, reimbursement
saquinavir
hiv protease inhibitors
adult
HIV-1
hiv infections
drug therapy, combination
treatment outcome
saquinavir
hiv protease inhibitors
evaluation of the transparency committee
---
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14078a-fra.php
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14612a-fra.php
2010
Canada
French
English
Cardiotoxicity
saquinavir
hiv protease inhibitors
drug therapy, combination
ritonavir
adult
hiv infections
long qt syndrome
PR INTERVAL PROLONGED
saquinavir
pharmacovigilance note
Saquinavir Monomethanesulfonate
---
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14077a-fra.php
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14611a-fra.php
2010
Canada
French
English
Cardiotoxicity
saquinavir
continuity of patient care
hiv protease inhibitors
saquinavir
electrocardiography
long qt syndrome
drug therapy, combination
ritonavir
pharmacovigilance note
patient education handout
---
http://www.meddispar.fr/medicaments/3420843
2008
France
French
saquinavir
drug prescriptions
capsules
administration, oral
legislation, drug
saquinavir
drug information
---
http://www.meddispar.fr/medicaments/3659403
2008
France
French
administration, oral
saquinavir
tablets
drug prescriptions
legislation, drug
saquinavir
drug information
---
http://www.has-sante.fr/portail/display.jsp?id=c_399964
2004
France
evaluation of the transparency committee
saquinavir
capsules
---