Simeprevir - CISMeF

Preferred Label : Simeprevir;

MeSH definition : Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS.;

MeSH synonym : N-(17-(2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo(13.3.0.04,6)octadec-7-ene-4-carbonyl)(cyclopropyl)sulfonamide;

MeSH hyponym : TMC 435350; TMC 435; olysio; 435350, TMC; TMC435350; TMC-435350; 435, TMC; TMC435; TMC-435;

Wikipedia link : https://en.wikipedia.org/wiki/Simeprevir;

Is substance : O;

UNII : 9WS5RD66HZ;

Details

Origin ID

D000069616;

UMLS CUI

C2605855;

ATC code(s)
- simeprevir [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Product containing simeprevir (medicinal product) [SNOMED CT concept]
- Simeprevir [NCIt concept]
- Simeprevir [LOINC component]
- Simeprevir [ICD-11 Extension code]
Currated CISMeF NLP mapping
- simeprevir [International Nonproprietary Name]
Exact mapping(s) to DCI
- simeprevir [International Nonproprietary Name]
Metaterm(s)
- hepatology [CISMeF Metaterm]
Pharmacological action(s)
- antiviral agents [MeSH Descriptor]
- protease inhibitors [MeSH Descriptor]
Record concept(s)
- TMC 435 [MeSH concept]
- TMC 435350 [MeSH concept]
- olysio [MeSH concept]
- simeprevir [MeSH concept]
See also inter- (CISMeF)
- chronic hepatitis C genotype 1 [Disease (Nov.)]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing simeprevir (medicinal product) [SNOMED CT concept]
- Simeprevir [NCIt concept]
- Simeprevir [LOINC component]
- Simeprevir (substance) [SNOMED CT concept]
- simeprevir [ATC Code]
- simeprevir [International Nonproprietary Name]
Validated automatic mappings to BTNT
- simeprevir [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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