Preferred Label : pigment epithelium-derived factor;
MeSH note : neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma
cells; has been shown to be the most potent inhibitor of angiogenesis in the mammalian
eye; from cultured pigment epithelial cells of the fetal retina; extracellular neurotrophic
protein belonging to the serpin family; amino acid sequence given in first source;
also found in fibroblast-like cells; RefSeq NM_002615 (human), NM_011340 (mouse),
NM_177927 (rat); do not confuse with EPC1 protein, an enhancer of polycomb homolog
1 protein;
CISMeF synonym : SERPINF1 protein, human; Serpinf1 protein, mouse; Serpinf1 protein, rat;
MeSH synonym : early population doubling level cDNA-1 protein; early population doubling level protein; SERPIN-F1; early PDL protein;
MeSH hyponym : Sdf3 protein, mouse; serine (or cysteine) proteinase inhibitor, clade F, member 1 protein, mouse; Pedfl protein, mouse; alpha-2 antiplasmin protein, mouse; Pedf protein, mouse; pigment epithelium derived factor protein, mouse; pigment epithelium-derived factor protein, rat; Dmrs91 protein, rat; serine (or cysteine) proteinase inhibitor, clade F, member 1 protein, rat; alpha-2 antiplasmin protein, rat; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium
derived factor), member 1 protein, human; PEDF protein, human;
Is substance : O;
Origin ID : C079657;
UMLS CUI : C0213321;
MeSH term(s) associated for indexing
- Pharmacological action(s)
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
