Preferred Label : serpins;
MeSH definition : A family of serine proteinase inhibitors which are similar in amino acid sequence
and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes.
This family includes alpha 1-antitrypsin, angiotensinogen, ovalbumin, antiplasmin,
alpha 1-antichymotrypsin, thyroxine-binding protein, complement 1 inactivators, antithrombin
III, heparin cofactor II, plasminogen inactivators, gene Y protein, placental plasminogen
activator inhibitor, and barley Z protein. Some members of the serpin family may be
substrates rather than inhibitors of SERINE ENDOPEPTIDASES, and some serpins occur
in plants where their function is not known.; A family of serine proteinase inhibitors which are similar in amino acid sequence
and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes.
Some members of the serpin family may be substrates rather than inhibitors of SERINE
ENDOPEPTIDASES.; A family of serine proteinase inhibitors which are similar in amino acid sequence
and mechanism of inhibition but differ in their specificity toward proteolytic enzymes.
Some members of the serpin family may be substrates rather than inhibitors of SERINE
ENDOPEPTIDASES.;
MeSH synonym : Serpin Protease Inhibitors; Inhibitors, Serpin Protease; Protease Inhibitors, Serpin; Serpin Peptidase Inhibitors; Inhibitors, Serpin Peptidase; Peptidase Inhibitors, Serpin; Serpin;
MeSH Hyperonym : serpin superfamily; Superfamily, Serpin;
MeSH annotation : a family of SERine Proteinase INhibitors, thus the source of the name;
Wikipedia link : https://en.wikipedia.org/wiki/Serpins;
Is substance : O;
Origin ID : D015843;
UMLS CUI : C0036764;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- LEX 032 [MeSH Supplementary Concept]
- caspin [MeSH Supplementary Concept]
- leupin [MeSH Supplementary Concept]
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
A family of serine proteinase inhibitors which are similar in amino acid sequence
and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes.
This family includes alpha 1-antitrypsin, angiotensinogen, ovalbumin, antiplasmin,
alpha 1-antichymotrypsin, thyroxine-binding protein, complement 1 inactivators, antithrombin
III, heparin cofactor II, plasminogen inactivators, gene Y protein, placental plasminogen
activator inhibitor, and barley Z protein. Some members of the serpin family may be
substrates rather than inhibitors of SERINE ENDOPEPTIDASES, and some serpins occur
in plants where their function is not known.
A family of serine proteinase inhibitors which are similar in amino acid sequence
and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes.
Some members of the serpin family may be substrates rather than inhibitors of SERINE
ENDOPEPTIDASES.
A family of serine proteinase inhibitors which are similar in amino acid sequence
and mechanism of inhibition but differ in their specificity toward proteolytic enzymes.
Some members of the serpin family may be substrates rather than inhibitors of SERINE
ENDOPEPTIDASES.
