interleukin-1beta-converting enzyme inhibitor

Preferred Label : interleukin-1beta-converting enzyme inhibitor;

MeSH note : encoded by the crmA gene (cytokine response modifier gene); prevents the proteolytic activation of IL-1, thereby suppressing an IL-1beta response to infection; amino acid sequence has been determined; cytokine response modifier A a strategically deployed viral weapon;

CISMeF synonym : 38K protein; SPI-2 cysteine proteinase inhibitor; crma protein, cowpox virus;

MeSH synonym : IL-1-CEI; Crma protein; ICE-I protein; IL-1beta converting enzyme inhibitor; caspase-1 inhibitor;

MeSH hyponym : SPI-2 protein, Cowpox virus; serine proteinase inhibitor 2 protein, Cowpox virus; Serp-2 protein, Cowpox virus; cytokine response modifier protein, Cowpox virus; hemorrhage-inducing 38 kDa protein, Cowpox virus;

Registry Number MeSH : 96282-35-8;

Is substance : O;

Details

Origin ID

C074641;

UMLS CUI

C0168318;

MeSH indexing information
- cysteine proteinase inhibitors [MeSH Descriptor]
MeSH term(s) associated for indexing
- serpins [MeSH Descriptor]
- viral proteins [MeSH Descriptor]
Record concept(s)
- SPI-2 cysteine proteinase inhibitor [MeSH concept]
- crma protein, cowpox virus [MeSH concept]
- interleukin-1beta-converting enzyme inhibitor [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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