Pigment Epithelium-Derived Factor

Preferred Label : Pigment Epithelium-Derived Factor;

NCIt synonyms : EPC-1; Proliferation-Inducing Protein 35; Cell Proliferation-Inducing Gene 35 Protein; Serpin F1; PEDF; SERPINF1;

NCIt definition : Pigment epithelium-derived factor (418 aa, 46 kDa) is encoded by the human SERPINF1 gene. This protein is involved in the regulation of both cell proliferation and angiogenesis.;

NCIt note : Pigment epithelium-derived factor does not have serine proteinase inhibitory activity. (UniProt);

Details

Origin ID

C101645;

UMLS CUI

C1528286;

OMIM relation
- Serpin peptidase inhibitor, clade f, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SERPINF1 protein, human [MeSH concept]
- pigment epithelium-derived factor [MeSH Supplementary Concept]
- pigment epithelium-derived factor [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SERPINF1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Negative Regulation of Angiogenesis [NCIt concept]
- Neural Development [NCIt concept]

Keyword's position in hierarchy(ies) :

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