rupintrivir - CISMeF

Preferred Label : rupintrivir;

MeSH note : a rhinovirus 3C protease inhibitor; structure in first source;

CISMeF synonym : AG 7088; (trans-(4S,2'R,5'S,3''S)-4-(2'-4-(4-fluorobenzyl)-6'-methyl-5'-((5''-methylisoxazole)-3''-carbonylamino)-4-oxoheptanoylamino))-5-(2''-oxopyrrolidin-3'''-yl)pent-2-enoic acid ethyl ester; ethyl-3-((5'-methylisoxazole-3'-carbonyl)-Valpsi(COCH2)Phe(4-F)-(pyrrol-Ala))propenoate;

MeSH synonym : ruprintrivir; 4-(((2R,5S)-2-((4-fluorophenyl)methyl)-6-methyl-5-(((5-methyl-3-isoxazolyl)carbonyl)amino)-1,4-dioxoheptyl)amino)-5-((3S)-2-oxo-3-pyrrolidinyl)-, ethyl ester, (2E,4S)-2-pentenoic acid;

MeSH hyponym : AG7088; AG-7088;

MeSH CAS label : 2-Pentenoic acid, 4-(((2R,5S)-2-((4-fluorophenyl)methyl)-6-methyl-5-(((5-methyl-3-isoxazolyl)carbonyl)amino)-1,4-dioxoheptyl)amino)-5-((3S)-2-oxo-3-pyrrolidinyl)-, ethyl ester, (2E,4S)-;

Is substance : O;

UNII : RGE5K1Q5QW;

Details

Origin ID

C118874;

UMLS CUI

C2350739;

Currated CISMeF NLP mapping
- Rupintrivir [NCIt concept]
MeSH term(s) associated for indexing
- isoxazoles [MeSH Descriptor]
- phenylalanine [MeSH Descriptor]
- pyrrolidinones [MeSH Descriptor]
- valine [MeSH Descriptor]
Pharmacological action(s)
- antiviral agents [MeSH Descriptor]
- protease inhibitors [MeSH Descriptor]
Record concept(s)
- (trans-(4S,2'R,5'S,3''S)-4-(2'-4-(4-fluorobenzyl)-6'-methyl-5'-((5''-methylisoxazole)-3''-carbonylamino)-4-oxoheptanoylamino))-5-(2''-oxopyrrolidin-3'''-yl)pent-2-enoic acid ethyl ester [MeSH concept]
- AG 7088 [MeSH concept]
- ethyl-3-((5'-methylisoxazole-3'-carbonyl)-Valpsi(COCH2)Phe(4-F)-(pyrrol-Ala))propenoate [MeSH concept]
- rupintrivir [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Rupintrivir [NCIt concept]

Keyword's position in hierarchy(ies) :

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