Enzyme Inhibition

Preferred Label : Enzyme Inhibition;

NCIt definition : Enzyme Inhibition involves interference with, or restraint of, the function of a biological molecule that possesses catalytic activity.;

Détails

Origin ID

C40577;

UMLS CUI

C1524081;

Currated CISMeF NLP mapping
- Enzyme inhibition [MedDRA Preferred Term]
Semantic type(s)
- Physiologic Function [UMLS semantic type]
biological_process_involves_gene_product
- Alpha-1-Antichymotrypsin [NCIt concept]
- Alpha-1-Antitrypsin [NCIt concept]
- Alpha-2-Antiplasmin [NCIt concept]
- Alpha-2-Macroglobulin [NCIt concept]
- Amyloid-Beta Precursor Protein [NCIt concept]
- Antileukoproteinase [NCIt concept]
- Antithrombin-III [NCIt concept]
- Apolipoprotein C-I [NCIt concept]
- Apolipoprotein C-III [NCIt concept]
- Apolipoprotein(a) [NCIt concept]
- Bradykinin [NCIt concept]
- Calcineurin-Binding Protein Cabin-1 [NCIt concept]
- Cystatin-A [NCIt concept]
- Cystatin-B [NCIt concept]
- Cystatin-C [NCIt concept]
- Cystatin-D [NCIt concept]
- Cystatin-M [NCIt concept]
- Cystatin-S [NCIt concept]
- Cystatin-SA [NCIt concept]
- Cystatin-SN [NCIt concept]
- EZH Inhibitory Protein [NCIt concept]
- Elafin [NCIt concept]
- Enzyme Inhibitor Protein [NCIt concept]
- Glucokinase Regulatory Protein [NCIt concept]
- Heparin Cofactor 2 [NCIt concept]
- Inter-Alpha-Trypsin Inhibitor Light Chain [NCIt concept]
- KNG1 Gene Product [NCIt concept]
- Kininogen-1 [NCIt concept]
- Kunitz-Type Protease Inhibitor 1 [NCIt concept]
- Lactotransferrin [NCIt concept]
- Metalloproteinase Inhibitor 1 [NCIt concept]
- Metalloproteinase Inhibitor 2 [NCIt concept]
- Metalloproteinase Inhibitor 3 [NCIt concept]
- Metalloproteinase Inhibitor 4 [NCIt concept]
- PIN2/TERF1-Interacting Telomerase Inhibitor 1 [NCIt concept]
- Pancreatic Secretory Trypsin Inhibitor [NCIt concept]
- Plasma Protease C1 Inhibitor [NCIt concept]
- Plasma Serine Protease Inhibitor [NCIt concept]
- Plasminogen Activator Inhibitor [NCIt concept]
- Plasminogen Activator Inhibitor 1 [NCIt concept]
- Plasminogen Activator Inhibitor 2 [NCIt concept]
- Protein CIP2A [NCIt concept]
- Protein SET [NCIt concept]
- Ribonuclease Inhibitor [NCIt concept]
- Serine Protease Inhibitor Kazal-Type 5 [NCIt concept]
- Serine Proteinase Inhibitor Protein [NCIt concept]
- Serpin A12 [NCIt concept]
- Serpin A9 [NCIt concept]
- Serpin B3 [NCIt concept]
- Serpin B4 [NCIt concept]
- Serpin B9 [NCIt concept]
- Serpin I2 [NCIt concept]
- TP53-Regulated Inhibitor of Apoptosis 1 [NCIt concept]
- Tissue Factor Pathway Inhibitor [NCIt concept]
- Tissue Factor Pathway Inhibitor 2 [NCIt concept]
- Tissue Inhibitor of Metalloproteinases [NCIt concept]
- Trypstatin [NCIt concept]
- Unconventional Prefoldin RPB5 Interactor 1 [NCIt concept]
- WAP Four-Disulfide Core Domain Protein 2 [NCIt concept]
is_mechanism_of_action_of_chemical_or_drug
- 5-Fluoro-2-Deoxycytidine [NCIt concept]
- 7-Hydroxystaurosporine [NCIt concept]
- Aerosol Gemcitabine [NCIt concept]
- Alvocidib [NCIt concept]
- Alvocidib Hydrochloride [NCIt concept]
- Aminocamptothecin [NCIt concept]
- Atorvastatin [NCIt concept]
- Atorvastatin Calcium [NCIt concept]
- Atorvastatin Sodium [NCIt concept]
- Azacitidine [NCIt concept]
- BMS-214662 [NCIt concept]
- BRAF V600E Degrader CFT1946 [NCIt concept]
- BRAF V600E Inhibitor HLX208 [NCIt concept]
- BRAF(V600E) Kinase Inhibitor ABM-1310 [NCIt concept]
- BRAF(V600E) Kinase Inhibitor RO5212054 [NCIt concept]
- Becatecarin [NCIt concept]
- Belinostat [NCIt concept]
- Belotecan Hydrochloride [NCIt concept]
- Benzoylphenylurea [NCIt concept]
- Brimarafenib [NCIt concept]
- Bryostatin 1 [NCIt concept]
- Buthionine Sulfoximine [NCIt concept]
- CDK Inhibitor AT7519 [NCIt concept]
- CDK Inhibitor R547 [NCIt concept]
- CDK Inhibitor SNS-032 [NCIt concept]
- CDK2/4/6/FLT3 Inhibitor FN-1501 [NCIt concept]
- CDK7 Inhibitor LY3405105 [NCIt concept]
- CDK7 Inhibitor LY3405105 Besylate [NCIt concept]
- CDK7 Inhibitor SY-5609 [NCIt concept]
- CDK7 Inhibitor TY-2699a [NCIt concept]
- CDK8/19 Inhibitor RVU120 [NCIt concept]
- CDK9 Inhibitor PRT2527 [NCIt concept]
- CK1alpha/CDK7/CDK9 Inhibitor BTX-A51 [NCIt concept]
- Cedazuridine [NCIt concept]
- Celecoxib [NCIt concept]
- Chloroquinoxaline Sulfonamide [NCIt concept]
- Claturafenib [NCIt concept]
- Cyclin-Dependent Kinase 7 Inhibitor [NCIt concept]
- Daporinad [NCIt concept]
- Decitabine [NCIt concept]
- Dihydro-5-Azacytidine [NCIt concept]
- ERB-38 Immunotoxin [NCIt concept]
- Edatrexate [NCIt concept]
- Eflornithine [NCIt concept]
- Eniluracil/5-FU Combination Tablet [NCIt concept]
- Enitociclib [NCIt concept]
- Etanidazole [NCIt concept]
- Fadraciclib [NCIt concept]
- Fermented Wheat Germ Extract [NCIt concept]
- Fidaxomicin [NCIt concept]
- Filanesib [NCIt concept]
- Firtecan Pegol [NCIt concept]
- Floxuridine [NCIt concept]
- Fludarabine Phosphate [NCIt concept]
- Fosgemcitabine Palabenamide [NCIt concept]
- Gemcitabine [NCIt concept]
- Gemcitabine Elaidate [NCIt concept]
- Gemcitabine Hydrochloride [NCIt concept]
- Gemcitabine Hydrochloride Emulsion [NCIt concept]
- Gemcitabine Liposome FF-10832 [NCIt concept]
- Gemcitabine Prodrug LY2334737 [NCIt concept]
- Gemcitabine-Releasing Intravesical System [NCIt concept]
- Gimatecan [NCIt concept]
- Hydroxyurea [NCIt concept]
- Ibuprofen Injection [NCIt concept]
- Idronoxil Suppository NOX66 [NCIt concept]
- Incyclinide [NCIt concept]
- Irinotecan [NCIt concept]
- Irinotecan Hydrochloride [NCIt concept]
- Isotretinoin [NCIt concept]
- Ispinesib [NCIt concept]
- Istisociclib [NCIt concept]
- KSP Inhibitor AZD4877 [NCIt concept]
- Liposomal Curcumin [NCIt concept]
- Lodenosine [NCIt concept]
- Mercaptopurine [NCIt concept]
- Mevociclib [NCIt concept]
- Mocaciclib [NCIt concept]
- Mocetinostat [NCIt concept]
- Nelarabine [NCIt concept]
- O6-Benzylguanine [NCIt concept]
- Oral Fludarabine Phosphate [NCIt concept]
- Oral Irinotecan Hydrochloride Formulation VAL-413 [NCIt concept]
- Oral Sodium Phenylbutyrate [NCIt concept]
- Oral Topotecan Hydrochloride [NCIt concept]
- Palbociclib [NCIt concept]
- Palbociclib Isethionate [NCIt concept]
- Panobinostat [NCIt concept]
- Panobinostat Lactate [NCIt concept]
- Pegylated Liposomal Irinotecan [NCIt concept]
- Pentostatin [NCIt concept]
- Perifosine [NCIt concept]
- Perillyl Alcohol [NCIt concept]
- Polyethyleneglycol-7-ethyl-10-hydroxycamptothecin DFP-13318 [NCIt concept]
- RNR Inhibitor BBI-825 [NCIt concept]
- RNR Inhibitor COH29 [NCIt concept]
- RNR Subunits Interaction Inhibitor TAS1553 [NCIt concept]
- Raltitrexed [NCIt concept]
- Rebimastat [NCIt concept]
- Ridaforolimus [NCIt concept]
- Riviciclib [NCIt concept]
- Roducitabine [NCIt concept]
- Romidepsin [NCIt concept]
- Safingol [NCIt concept]
- Safingol Hydrochloride [NCIt concept]
- Sapacitabine [NCIt concept]
- Saracatinib Difumarate [NCIt concept]
- Seliciclib [NCIt concept]
- Selumetinib [NCIt concept]
- Selumetinib Sulfate [NCIt concept]
- Sendegobresib [NCIt concept]
- Shark Cartilage [NCIt concept]
- Shark Cartilage Extract AE-941 [NCIt concept]
- Silatecan AR-67 [NCIt concept]
- Sodium Phenylbutyrate [NCIt concept]
- Sorafenib Tosylate [NCIt concept]
- Sparfosic Acid [NCIt concept]
- Tacaciclib [NCIt concept]
- Talotrexin [NCIt concept]
- Talotrexin Ammonium [NCIt concept]
- Tambiciclib [NCIt concept]
- Tanuxiciclib [NCIt concept]
- Tegafur-Gimeracil-Oteracil Potassium-Leucovorin Calcium Oral Formulation [NCIt concept]
- Tegafur-gimeracil-oteracil Potassium [NCIt concept]
- Temsirolimus [NCIt concept]
- Tenifatecan [NCIt concept]
- Tetrahydrouridine [NCIt concept]
- Thioguanine [NCIt concept]
- Tiazofurin [NCIt concept]
- Tilarginine [NCIt concept]
- Tipifarnib [NCIt concept]
- Topoisomerase-II Inhibitor Racemic XK469 [NCIt concept]
- Topotecan Hydrochloride [NCIt concept]
- Triapine [NCIt concept]
- Tributyrin [NCIt concept]
- Vemurafenib [NCIt concept]
- Vorinostat [NCIt concept]
- Zeltociclib [NCIt concept]
- Zemirciclib [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- Aurora Kinase Inhibitor AMG 900 [NCIt concept]
- Aurora Kinase Inhibitor SNS-314 [NCIt concept]
- Axl/Mer Inhibitor INCB081776 [NCIt concept]
- Axl/Mer Inhibitor PF-07265807 [NCIt concept]
- BMX Inhibitor [NCIt concept]
- Dexrazoxane [NCIt concept]
- Dexrazoxane Hydrochloride [NCIt concept]
- Erlotinib Hydrochloride [NCIt concept]
- Ibrutinib [NCIt concept]
- Multikinase Inhibitor AT9283 [NCIt concept]
- Polo-like Kinase 1 Inhibitor GSK461364 [NCIt concept]
- Polo-like Kinase 1 Inhibitor MK1496 [NCIt concept]
- Rigosertib Sodium [NCIt concept]
- Semaxanib [NCIt concept]
- Tinengotinib [NCIt concept]
- Varlitinib [NCIt concept]
- Varlitinib Tosylate [NCIt concept]
process_involves_gene
- A2M Gene [NCIt concept]
- A2M wt Allele [NCIt concept]
- AGT Gene [NCIt concept]
- AGT wt Allele [NCIt concept]
- AMBP Gene [NCIt concept]
- AMBP wt Allele [NCIt concept]
- APOC1 Gene [NCIt concept]
- APOC1 wt Allele [NCIt concept]
- APOC3 Gene [NCIt concept]
- APOC3 wt Allele [NCIt concept]
- CABIN1 Gene [NCIt concept]
- CABIN1 wt Allele [NCIt concept]
- CIP2A Gene [NCIt concept]
- CIP2A wt Allele [NCIt concept]
- CST1 Gene [NCIt concept]
- CST1 wt Allele [NCIt concept]
- CST2 Gene [NCIt concept]
- CST2 wt Allele [NCIt concept]
- CST3 Gene [NCIt concept]
- CST3 wt Allele [NCIt concept]
- CST4 Gene [NCIt concept]
- CST4 wt Allele [NCIt concept]
- CST5 Gene [NCIt concept]
- CST5 wt Allele [NCIt concept]
- CST6 Gene [NCIt concept]
- CST6 wt Allele [NCIt concept]
- CSTA Gene [NCIt concept]
- CSTA wt Allele [NCIt concept]
- CSTB Gene [NCIt concept]
- CSTB wt Allele [NCIt concept]
- Cystatin Family Gene [NCIt concept]
- Cystatin Superfamily Gene [NCIt concept]
- Cysteine Proteinase Inhibitor Gene [NCIt concept]
- EZHIP Gene [NCIt concept]
- EZHIP wt Allele [NCIt concept]
- Enzyme Inhibitor Gene [NCIt concept]
- GCKR Gene [NCIt concept]
- GCKR wt Allele [NCIt concept]
- KNG1 Gene [NCIt concept]
- KNG1 wt Allele [NCIt concept]
- Kininogen Family Gene [NCIt concept]
- LPA Gene [NCIt concept]
- LPA wt Allele [NCIt concept]
- LTF Gene [NCIt concept]
- LTF wt Allele [NCIt concept]
- PI3 Gene [NCIt concept]
- PI3 wt Allele [NCIt concept]
- PINX1 Gene [NCIt concept]
- PINX1 wt Allele [NCIt concept]
- Proteinase Inhibitor Gene [NCIt concept]
- RNH1 Gene [NCIt concept]
- RNH1 wt Allele [NCIt concept]
- SERPINA1 Gene [NCIt concept]
- SERPINA1 wt Allele [NCIt concept]
- SERPINA12 Gene [NCIt concept]
- SERPINA12 wt Allele [NCIt concept]
- SERPINA3 Gene [NCIt concept]
- SERPINA3 wt Allele [NCIt concept]
- SERPINA5 Gene [NCIt concept]
- SERPINA5 wt Allele [NCIt concept]
- SERPINA9 Gene [NCIt concept]
- SERPINA9 wt Allele [NCIt concept]
- SERPINB2 Gene [NCIt concept]
- SERPINB2 wt Allele [NCIt concept]
- SERPINB3 Gene [NCIt concept]
- SERPINB3 wt Allele [NCIt concept]
- SERPINB4 Gene [NCIt concept]
- SERPINB4 wt Allele [NCIt concept]
- SERPINB9 Gene [NCIt concept]
- SERPINB9 wt Allele [NCIt concept]
- SERPINC1 Gene [NCIt concept]
- SERPINC1 wt Allele [NCIt concept]
- SERPIND1 Gene [NCIt concept]
- SERPIND1 wt Allele [NCIt concept]
- SERPINE1 Gene [NCIt concept]
- SERPINE1 wt Allele [NCIt concept]
- SERPINF2 Gene [NCIt concept]
- SERPINF2 wt Allele [NCIt concept]
- SERPING1 Gene [NCIt concept]
- SERPING1 wt Allele [NCIt concept]
- SERPINI2 Gene [NCIt concept]
- SERPINI2 wt Allele [NCIt concept]
- SET Gene [NCIt concept]
- SET wt Allele [NCIt concept]
- SLPI Gene [NCIt concept]
- SLPI wt Allele [NCIt concept]
- SPINK1 Gene [NCIt concept]
- SPINK1 wt Allele [NCIt concept]
- SPINK5 Gene [NCIt concept]
- SPINK5 wt Allele [NCIt concept]
- SPINT1 Gene [NCIt concept]
- SPINT1 wt Allele [NCIt concept]
- Stefin Family Gene [NCIt concept]
- TFPI Gene [NCIt concept]
- TFPI wt Allele [NCIt concept]
- TFPI2 Gene [NCIt concept]
- TFPI2 wt Allele [NCIt concept]
- TIMP1 Gene [NCIt concept]
- TIMP1 wt Allele [NCIt concept]
- TIMP2 Gene [NCIt concept]
- TIMP2 wt Allele [NCIt concept]
- TIMP3 Gene [NCIt concept]
- TIMP3 wt Allele [NCIt concept]
- TIMP4 Gene [NCIt concept]
- TIMP4 wt Allele [NCIt concept]
- TRIAP1 Gene [NCIt concept]
- TRIAP1 wt Allele [NCIt concept]
- URI1 Gene [NCIt concept]
- URI1 wt Allele [NCIt concept]
- WFDC1 Gene [NCIt concept]
- WFDC1 wt Allele [NCIt concept]
- WFDC2 Gene [NCIt concept]
- WFDC2 wt Allele [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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