Preferred Label : Tributyrin;
NCIt synonyms : Butyryl Triglyceride; Glyceryl Tributyrate; 1,2,3-Propanetriyl Butanoate; Butanoic Acid 1,2,3-Propanetriyl Ester; TB;
NCIt related terms : Butanoic Acid, 1,2,3-Propanetriyl Ester; 1,2,3-Tributyrylglycerol;
NCIt definition : A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate,
the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased
differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some
tumor cell lines. (NCI04);
Alternative definition : NCI-GLOSS: A triglyceride drug that may inhibit cell growth and induce cell differentiation.
Differentiating agents may be effective in changing cancer cells back into normal
cells.;
UNII : S05LZ624MF;
InChIKey : UYXTWWCETRIEDR-UHFFFAOYSA-N;
CAS number : 60-01-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 60-01-5
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G-SRS /a ;
Chemical formula : C15H26O6;
NSC code : 661583;
Codes from synonyms : 04044; NSC0661583; CDR0000045443;
Origin ID : C1260;
UMLS CUI : C0077025;
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- chemical_or_drug_affects_gene_product
- chemical_or_drug_has_mechanism_of_action
- chemical_or_drug_has_physiologic_effect
- concept_is_in_subset