Negative Regulation of Cell Cycle

Preferred Label : Negative Regulation of Cell Cycle;

NCIt synonyms : Cell Cycle Inhibition; Cell Cycle Arrest;

NCIt definition : An interruption in the periodic biochemical and structural events occurring during proliferation of cells such as in tissue culture; the cycle is divided into periods called: G0, Gap1 (G1), synthesis (S1), Gap2 (G2), and mitosis (M). The period runs from one division to the next.;

Details

Origin ID

C18824;

UMLS CUI

C1516332;

Automatic exact mappings (from CISMeF team)
- M phase cell cycle checkpoints [MeSH Descriptor]
- cell cycle checkpoints [MeSH Descriptor]
Currated CISMeF NLP mapping
- cell cycle arrest [GO term]
- cell cycle arrest [MeSH concept]
- negative regulation of cell cycle [GO term]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- negative regulation of cell cycle [GO term]
biological_process_has_associated_location
- Cell [NCIt concept]
biological_process_has_initiator_chemical_or_drug
- Mitogen [NCIt concept]
biological_process_has_initiator_process
- Intercellular Communication Process [NCIt concept]
biological_process_involves_gene_product
- 14-3-3 Protein Sigma [NCIt concept]
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 [NCIt concept]
- Apoptosis-Stimulating of p53 Protein 1 [NCIt concept]
- BMP/Retinoic Acid-Inducible Neural-Specific Protein 1 [NCIt concept]
- BMP/Retinoic Acid-Inducible Neural-Specific Protein 3 [NCIt concept]
- Bromodomain-Containing Protein 7 [NCIt concept]
- Cell Division Cycle and Apoptosis Regulator Protein 1 [NCIt concept]
- Claspin [NCIt concept]
- Cyclin-Dependent Kinase 4 Inhibitor B [NCIt concept]
- Cyclin-Dependent Kinase 6 [NCIt concept]
- DNA Damage-Inducible Transcript 3 Protein [NCIt concept]
- Dual Specificity Mitogen-Activated Protein Kinase Kinase 6 [NCIt concept]
- Forkhead Box Protein N3 [NCIt concept]
- Geminin [NCIt concept]
- Growth Arrest-Specific Protein 6 [NCIt concept]
- Growth Arrest-Specific Protein 7 [NCIt concept]
- Histone-Lysine N-Methyltransferase 2E [NCIt concept]
- Interferon Regulatory Factor 6 [NCIt concept]
- Interleukin-24 [NCIt concept]
- KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 1 [NCIt concept]
- Melanoma-Associated Antigen D1 [NCIt concept]
- Myeloid Leukemia Factor 1 [NCIt concept]
- PR Domain Zinc Finger Protein 4 [NCIt concept]
- Protein Mdm4 [NCIt concept]
- Protein Phosphatase 1 Regulatory Subunit 15A [NCIt concept]
- Protein Reprimo [NCIt concept]
- Protein Tob2 [NCIt concept]
- RNA-Binding Protein 38 [NCIt concept]
- Ribosomal Protein S6 Kinase Alpha-2 [NCIt concept]
- Serine/Threonine-Protein Kinase Chk1 [NCIt concept]
- Target of Rapamycin Complex Subunit LST8 [NCIt concept]
- Telomere-Associated Protein RIF1 [NCIt concept]
- Wings Apart-Like Protein Homolog [NCIt concept]
- Zinc Finger Protein PLAGL1 [NCIt concept]
biological_process_is_part_of_process
- Cell Proliferation [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- Betulinic Acid [NCIt concept]
- CDK Inhibitor AT7519 [NCIt concept]
- CDK2/4/6/FLT3 Inhibitor FN-1501 [NCIt concept]
- CDK7 Inhibitor LY3405105 [NCIt concept]
- CDK7 Inhibitor LY3405105 Besylate [NCIt concept]
- CDK8/19 Inhibitor RVU120 [NCIt concept]
- Cevipabulin [NCIt concept]
- E2F1 Pathway Activator ARQ 171 [NCIt concept]
- Eribulin [NCIt concept]
- Eribulin Mesylate [NCIt concept]
- Fadraciclib [NCIt concept]
- Filanesib [NCIt concept]
- Folate Receptor-Targeted Vinca Alkaloid/Mitomycin C EC0225 [NCIt concept]
- Ispinesib [NCIt concept]
- KSP Inhibitor AZD4877 [NCIt concept]
- Riviciclib [NCIt concept]
- Tributyrin [NCIt concept]
- Vintafolide [NCIt concept]
process_involves_gene
- BRD7 Gene [NCIt concept]
- BRD7 wt Allele [NCIt concept]
- BRINP1 Gene [NCIt concept]
- BRINP1 wt Allele [NCIt concept]
- BRINP3 Gene [NCIt concept]
- BRINP3 wt Allele [NCIt concept]
- CCAR1 Gene [NCIt concept]
- CCAR1 wt Allele [NCIt concept]
- CDK6 Gene [NCIt concept]
- CDK6 wt Allele [NCIt concept]
- CDKN2B Gene [NCIt concept]
- CDKN2B wt Allele [NCIt concept]
- CHEK1 Gene [NCIt concept]
- CHEK1 wt Allele [NCIt concept]
- CLSPN Gene [NCIt concept]
- CLSPN wt Allele [NCIt concept]
- DDIT3 Gene [NCIt concept]
- DDIT3 wt Allele [NCIt concept]
- FOXN3 Gene [NCIt concept]
- FOXN3 wt Allele [NCIt concept]
- GAS6 Gene [NCIt concept]
- GAS6 wt Allele [NCIt concept]
- GAS7 Gene [NCIt concept]
- GAS7 wt Allele [NCIt concept]
- GMNN Gene [NCIt concept]
- GMNN wt Allele [NCIt concept]
- IL24 Gene [NCIt concept]
- IL24 wt Allele [NCIt concept]
- IRF6 Gene [NCIt concept]
- IRF6 wt Allele [NCIt concept]
- KHDRBS1 Gene [NCIt concept]
- KHDRBS1 wt Allele [NCIt concept]
- KMT2E Gene [NCIt concept]
- KMT2E wt Allele [NCIt concept]
- MAGED1 Gene [NCIt concept]
- MAGED1 wt Allele [NCIt concept]
- MDM4 Gene [NCIt concept]
- MDM4 wt Allele [NCIt concept]
- MLF1 Gene [NCIt concept]
- MLF1 wt Allele [NCIt concept]
- MLST8 Gene [NCIt concept]
- MLST8 wt Allele [NCIt concept]
- PKMYT1 Gene [NCIt concept]
- PKMYT1 wt Allele [NCIt concept]
- PLAGL1 Gene [NCIt concept]
- PLAGL1 wt Allele [NCIt concept]
- PPP1R13B Gene [NCIt concept]
- PPP1R13B wt Allele [NCIt concept]
- PPP1R15A Gene [NCIt concept]
- PPP1R15A wt Allele [NCIt concept]
- PRDM4 Gene [NCIt concept]
- PRDM4 wt Allele [NCIt concept]
- PRKAA1 Gene [NCIt concept]
- PRKAA1 wt Allele [NCIt concept]
- RBM38 Gene [NCIt concept]
- RBM38 wt Allele [NCIt concept]
- RIF1 Gene [NCIt concept]
- RIF1 wt Allele [NCIt concept]
- RPRM Gene [NCIt concept]
- RPRM wt Allele [NCIt concept]
- RPS6KA2 Gene [NCIt concept]
- RPS6KA2 wt Allele [NCIt concept]
- SFN Gene [NCIt concept]
- SFN wt Allele [NCIt concept]
- TOB2 Gene [NCIt concept]
- TOB2 wt Allele [NCIt concept]
- WAPL Gene [NCIt concept]
- WAPL wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients