Growth Arrest-Specific Protein 6

Preferred Label : Growth Arrest-Specific Protein 6;

NCIt synonyms : GAS-6; AXL Stimulatory Factor; AXL Receptor Tyrosine Kinase Ligand; GAS6;

NCIt definition : Growth arrest-specific protein 6 (721 aa, 80 kDa) is encoded by the human GAS6 gene. This protein is involved in the modulation of receptor tyrosine kinase-dependent signaling.;

NCIt note : Growth arrest-specific protein 6 is a ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MERTK. (UniProt);

Details

Origin ID

C101631;

UMLS CUI

C1567829;

OMIM relation
- Growth arrest-specific 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GAS6 protein, human [MeSH concept]
- growth arrest-specific protein 6 [MeSH Supplementary Concept]
- growth arrest-specific protein 6 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- GAS6 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_has_chemical_classification
- Extracellular Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Leukocyte Trafficking Induction [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
is_target
- Batiraxcept [NCIt concept]

Keyword's position in hierarchy(ies) :

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