BRINP1 wt Allele

Preferred Label : BRINP1 wt Allele;

NCIt synonyms : DBCCR1; FAM5A; DBC1; DBCCR1 wt Allele; BA574M5.1 (Deleted In Bladder Cancer Chromosome Region Candidate 1 (IB3089A)) Gene; BA574M5.1; Deleted in Bladder Cancer Chromosome Region Candidate 1 Gene; IB3089A; BMP/Retinoic Acid Inducible Neural Specific 1 wt Allele; Deleted in Bladder Cancer 1 Gene;

NCIt definition : Human BRINP1 wild-type allele is located within 9q32-q33 and is approximately 203 kb in length. This allele, which encodes BMP/retinoic acid-inducible neural-specific protein 1, is involved in the modulation of cellular proliferation, the inhibition of the G1/S transition of the cell cycle, the mediation of non-apoptotic cell death and the regulation of the expression of components of the fibrinolysis pathway. Hypermethylation-based silencing or loss of homozygosity of the gene occurs in many cases of bladder cancer.;

GenBank Accession Number : AF027734;

Details

Origin ID

C54426;

UMLS CUI

C1705142;

OMIM relation
- Bone morphogenetic protein/retinoic acid-inducible neural-specific protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Bladder Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 9: 119211255-119008462 [NCIt concept]
gene_in_chromosomal_location
- 9q32-q33 [NCIt concept]
gene_is_biomarker_of
- Colorectal Carcinoma [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Positive Regulation of Cell Death [NCIt concept]

Keyword's position in hierarchy(ies) :

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