" /> Cevipabulin - CISMeF





Preferred Label : Cevipabulin;

NCIt synonyms : Cevipabulinum; Tubulin Binding Agent TTI-237; TTI 237;

NCIt related terms : TTI-237;

NCIt definition : A synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called mitotic inhibitors.;

UNII : P14M0DWS2J;

InChIKey : ZUZPCOQWSYNWLU-VIFPVBQESA-N;

CAS number : 849550-05-6;

Chemical formula : C18H18ClF5N6O;

Codes from synonyms : CDR0000438726;

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31/07/2025


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