BRINP3 wt Allele

Preferred Label : BRINP3 wt Allele;

NCIt synonyms : DBCCR1L; BMP/Retinoic Acid Inducible Neural Specific 3 wt Allele; FAM5C; DBCCR1L1; Family With Sequence Similarity 5, Member C Gene;

NCIt definition : Human BRINP3 wild-type allele is located in the vicinity of 1q31.1 and is approximately 381 kb in length. This allele, which encodes BMP/retinoic acid-inducible neural-specific protein 3, is involved in neuronal differentiation and cell cycle arrest. Aberrant expression of the gene may be associated with pituitary tumors, tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Hypermethylation of the gene may be a marker for gastric cancer.;

NCIt note : Mutation of the BRINP3 gene may be associated with diffuse large B-cell lymphoma (DLBCL). (Cell. 2017;171:481-494.e15.);

NCI Metathesaurus CUI : CL540333;

GenBank Accession Number : AB111893;

Details

Origin ID

C142376;

UMLS CUI

C4553362;

Automatic exact mappings (from CISMeF team)
- Bone morphogenetic protein/retinoic acid-inducible neural-specific protein 3 [OMIM gene]
OMIM relation
- Bone morphogenetic protein/retinoic acid-inducible neural-specific protein 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Bone morphogenetic protein/retinoic acid-inducible neural-specific protein 3 [OMIM gene]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Positive Regulation of Cell Differentiation [NCIt concept]

Keyword's position in hierarchy(ies) :

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