" /> Eribulin - CISMeF





Preferred Label : Eribulin;

NCIt synonyms : 2-(3-Amino-2-hydroxypropyl)hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)11,15-18,21-24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo(3,2-i)furo(2',3'-5,6)pyrano(4,3-b)(1,4)dioxacyclopentacosin-5-(4H)-one;

NCIt definition : An analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic activity. Eribulin binds to the vinca domain of tubulin and inhibits the polymerization of tubulin and the assembly of microtubules, resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest at G2/M phase, and, potentially, tumor regression.;

UNII : LR24G6354G;

InChIKey : UFNVPOGXISZXJD-JBQZKEIOSA-N;

CAS number : 253128-41-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 253128-41-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : ER-086526;

Chemical formula : C40H59NO11;

ChEBI ID : CHEBI:63587;

Codes from synonyms : 197;

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15/05/2024


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