PRKAA1 wt Allele

Preferred Label : PRKAA1 wt Allele;

NCIt synonyms : AMP-Activated Protein Kinase, Catalytic, Alpha-1 Gene; Protein Kinase, AMP-Activated, Catalytic, Alpha-1 Gene; AMPKa1; Protein Kinase, AMP-Activated, Alpha 1 Catalytic Subunit wt Allele; AMP-Activated, Catalytic, Alpha-1 Gene; AMPK; AMPK1;

NCIt definition : Human PRKAA1 wild-type allele is located in the vicinity of 5p12 and is approximately 39 kb in length. This allele, which encodes 5'-AMP-activated protein kinase catalytic subunit alpha-1 protein, plays a role in the modulation of many cellular processes through the phosphorylation of metabolic enzymes and transcription regulatory proteins.;

GenBank Accession Number : NM_006251;

Details

Origin ID

C116032;

UMLS CUI

C3890397;

Automatic exact mappings (from CISMeF team)
- AMP-Activated protein kinases [MeSH Descriptor]
- [acetyl-CoA carboxylase] kinase activity [GO term]
- [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity [GO term]
- cAMP-dependent protein kinase activity [GO term]
- protein kinase AMP-activated catalytic subunit alpha 1 [HGNC gene]
OMIM relation
- Protein kinase, amp-activated, catalytic, alpha-1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Autophagy Regulation Pathway [NCIt concept]
- ChREBP Pathway [NCIt concept]
- Circadian Rhythm Pathway KEGG [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Insulin Resistance Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Carbohydrate Metabolic Process [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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