Histone-Lysine N-Methyltransferase 2E

Preferred Label : Histone-Lysine N-Methyltransferase 2E;

NCIt synonyms : Myeloid/Lymphoid or Mixed-Lineage Leukemia Protein 5; EC 2.1.1.43; KMT2E; Lysine N-Methyltransferase 2E; Histone-Lysine N-Methyltransferase MLL5; MLL5;

NCIt definition : Histone-lysine N-methyltransferase MLL5 (1858 aa, 204 kDa) is encoded by the human MLL5 gene. This protein is involved in the methylation of histone proteins, the modulation of cell cycle progression and the regulation of gene transcription.;

Détails

Origin ID

C93096;

UMLS CUI

C1137844;

OMIM relation
- Lysine-specific methyltransferase 2e [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KMT2E protein, human [MeSH concept]
- KMT2E protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KMT2E Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- PHD Finger [NCIt concept]
- SET Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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