PLAGL1 wt Allele

Preferred Label : PLAGL1 wt Allele;

NCIt synonyms : ZAC; ZAC1; Pleiomorphic Adenoma Gene-Like 1 wt Allele; LOT1; ZAC Tumor Suppressor Gene; RP3-468K18.1;

NCIt definition : Human PLAGL1 wild-type allele is located within 6q24-q25 and is approximately 68 kb in length. This allele, which encodes zinc finger protein PLAGL1, is involved in the inhibition of cellular proliferation through induction of the p53 apoptosis and cell cycle arrest pathways.;

GenBank Accession Number : NM_002656;

Details

Origin ID

C51294;

UMLS CUI

C1709407;

OMIM relation
- Plag1-like zinc finger 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6q24-q25 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Ligand Binding [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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