MLST8 wt Allele

Preferred Label : MLST8 wt Allele;

NCIt synonyms : GBL; MTOR Associated Protein, LST8 Homolog (S. cerevisiae) Gene; GbetaL; MTOR Associated Protein, LST8 Homolog wt Allele; WAT1, S. pombe, Homolog of Gene; LTS8, S. cerevisiae, Homolog of Gene; POP3; POP3, S. pombe, Homolog of Gene; WAT1; LST8;

NCIt definition : Human MLST8 wild-type allele is located in the vicinity of 16p13.3 and is approximately 5 kb in length. This allele, which encodes target of rapamycin complex subunit LST8 protein, is involved in signaling mediated by both mTORC1 and mTORC2.;

NCI Metathesaurus CUI : CL1664810;

GenBank Accession Number : NM_022372;

Details

Origin ID

C181674;

UMLS CUI

C5551147;

Automatic exact mappings (from CISMeF team)
- Mtor-associated protein lst8 [OMIM gene]
- Popeye domain-containing protein 3 [OMIM gene]
OMIM relation
- Mtor-associated protein lst8 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 16p13.3 [NCIt concept]
gene_is_element_in_pathway
- Autophagy Regulation Pathway [NCIt concept]
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- LKB1 Signaling Pathway [NCIt concept]
- PI3K/AKT1 Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_plays_role_in_process
- Autophagy [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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