Autophagy - CISMeF

Preferred Label : Autophagy;

NCIt synonyms : Autophagocytosis;

NCIt definition : Autophagy is a biological process that involves the lysosomal degradation of intracellular components using it a cell's own machinery. This process can play a role in cellular defense, embryonic development, and cell growth.;

Alternative definition : NCI-GLOSS: A normal process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus), which may lead to cell death. Autophagy may prevent normal cells from developing into cancer cells, but it may also protect cancer cells by destroying anticancer drugs or substances taken up by them.;

Codes from synonyms : CDR0000561319;

Details

Origin ID

C71427;

UMLS CUI

C0004391;

Automatic exact mappings (from CISMeF team)
- macroautophagy [GO term]
Currated CISMeF NLP mapping
- autophagy [COVID-19 Thesaurus concept]
- autophagy [GO term]
- autophagy [MeSH Descriptor]
- autophagy [MeSH concept]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- autophagy [GO term]
- autophagy [MeSH concept]
- autophagy [MeSH Descriptor]
biological_process_has_associated_location
- Cell [NCIt concept]
biological_process_involves_gene_product
- Autophagy-Related Protein 13 [NCIt concept]
- Autophagy-Related Protein 16-1 [NCIt concept]
- BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 [NCIt concept]
- Beclin-1 [NCIt concept]
- Beclin-2 [NCIt concept]
- CDGSH Iron-Sulfur Domain-Containing Protein 2 [NCIt concept]
- Charged Multivesicular Body Protein 2b [NCIt concept]
- Cysteine Protease ATG4C [NCIt concept]
- Ectopic P Granules Protein 5 Homolog [NCIt concept]
- Endosome/Lysosome-Associated Apoptosis and Autophagy Regulator 1 [NCIt concept]
- GATOR Complex Protein DEPDC5 [NCIt concept]
- GATOR Complex Protein NPRL2 [NCIt concept]
- GATOR Complex Protein NPRL3 [NCIt concept]
- Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 2 [NCIt concept]
- Gamma-Interferon-Inducible Protein 16 [NCIt concept]
- Guanine Nucleotide Exchange Factor C9orf72 [NCIt concept]
- Heat Shock Protein Beta-8 [NCIt concept]
- Immunity-Related GTPase Family M Protein [NCIt concept]
- Intraflagellar Transport Protein 88 Homolog [NCIt concept]
- Lysosomal Acid Glucosylceramidase [NCIt concept]
- Lysosomal Protective Protein [NCIt concept]
- Microtubule-Associated Proteins 1A/1B Light Chain 3 [NCIt concept]
- Microtubule-Associated Proteins 1A/1B Light Chain 3A [NCIt concept]
- Microtubule-Associated Proteins 1A/1B Light Chain 3B [NCIt concept]
- Microtubule-Associated Proteins 1A/1B Light Chain 3C [NCIt concept]
- NPC Intracellular Cholesterol Transporter 1 [NCIt concept]
- NPC Intracellular Cholesterol Transporter 2 [NCIt concept]
- Optineurin [NCIt concept]
- Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3 [NCIt concept]
- Phosphofurin Acidic Cluster Sorting Protein 2 [NCIt concept]
- Protein C19orf12 [NCIt concept]
- Protein LYRIC [NCIt concept]
- Pyrin [NCIt concept]
- RB1-Inducible Coiled-Coil Protein 1 [NCIt concept]
- Ras-Related GTP-Binding Protein C [NCIt concept]
- Ras-Related Protein Rab-23 [NCIt concept]
- Ras-Related Protein Rab-39B [NCIt concept]
- Ras-Related Protein Rab-5A [NCIt concept]
- Run Domain Beclin-1-Interacting and Cysteine-Rich Domain-Containing Protein [NCIt concept]
- Serine/Threonine-Protein Kinase Pim-2 [NCIt concept]
- Serine/Threonine-Protein Kinase ULK1 [NCIt concept]
- Serine/Threonine-Protein Kinase ULK2 [NCIt concept]
- Synaptosomal-Associated Protein 29 [NCIt concept]
- Syntaxin-17 [NCIt concept]
- Target of Rapamycin Complex Subunit LST8 [NCIt concept]
- Transmembrane Protein 41B [NCIt concept]
- Tripartite Motif-Containing Protein 5 [NCIt concept]
- UV Radiation Resistance-Associated Gene Protein [NCIt concept]
- Ubiquitin Carboxyl-Terminal Hydrolase 13 [NCIt concept]
- Ubiquitin-Like Modifier-Activating Enzyme ATG7 [NCIt concept]
- Vacuolar Protein Sorting-Associated Protein 41 Homolog [NCIt concept]
- Vam6/Vps39-Like Protein [NCIt concept]
- Vesicle-Associated Membrane Protein 8 [NCIt concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
process_involves_gene
- ATG13 Gene [NCIt concept]
- ATG13 wt Allele [NCIt concept]
- ATG16L1 Gene [NCIt concept]
- ATG16L1 wt Allele [NCIt concept]
- ATG4C Gene [NCIt concept]
- ATG4C wt Allele [NCIt concept]
- ATG7 Gene [NCIt concept]
- ATG7 wt Allele [NCIt concept]
- BECN1 Gene [NCIt concept]
- BECN1 wt Allele [NCIt concept]
- BECN2 Gene [NCIt concept]
- BECN2 wt Allele [NCIt concept]
- BNIP3 Gene [NCIt concept]
- BNIP3 wt Allele [NCIt concept]
- C19orf12 Gene [NCIt concept]
- C19orf12 wt Allele [NCIt concept]
- C9orf72 Gene [NCIt concept]
- C9orf72 wt Allele [NCIt concept]
- CHMP2B Gene [NCIt concept]
- CHMP2B wt Allele [NCIt concept]
- CISD2 Gene [NCIt concept]
- CISD2 wt Allele [NCIt concept]
- CTSA Gene [NCIt concept]
- CTSA wt Allele [NCIt concept]
- DEPDC5 Gene [NCIt concept]
- DEPDC5 wt Allele [NCIt concept]
- ELAPOR1 Gene [NCIt concept]
- ELAPOR1 wt Allele [NCIt concept]
- EPG5 Gene [NCIt concept]
- EPG5 wt Allele [NCIt concept]
- GABARAPL2 Gene [NCIt concept]
- GABARAPL2 wt Allele [NCIt concept]
- GBA1 Gene [NCIt concept]
- GBA1 wt Allele [NCIt concept]
- HSPB8 Gene [NCIt concept]
- HSPB8 wt Allele [NCIt concept]
- IFI16 Gene [NCIt concept]
- IFI16 wt Allele [NCIt concept]
- IFT88 Gene [NCIt concept]
- IFT88 wt Allele [NCIt concept]
- IRGM Gene [NCIt concept]
- IRGM wt Allele [NCIt concept]
- MAP1LC3A Gene [NCIt concept]
- MAP1LC3A wt Allele [NCIt concept]
- MAP1LC3B Gene [NCIt concept]
- MAP1LC3B wt Allele [NCIt concept]
- MAP1LC3C Gene [NCIt concept]
- MAP1LC3C wt Allele [NCIt concept]
- MEFV Gene [NCIt concept]
- MEFV wt Allele [NCIt concept]
- MLST8 Gene [NCIt concept]
- MLST8 wt Allele [NCIt concept]
- NPC1 Gene [NCIt concept]
- NPC1 wt Allele [NCIt concept]
- NPC2 Gene [NCIt concept]
- NPC2 wt Allele [NCIt concept]
- NPRL2 Gene [NCIt concept]
- NPRL2 wt Allele [NCIt concept]
- OPTN Gene [NCIt concept]
- OPTN wt Allele [NCIt concept]
- PACS2 Gene [NCIt concept]
- PACS2 wt Allele [NCIt concept]
- PIK3C3 Gene [NCIt concept]
- PIK3C3 wt Allele [NCIt concept]
- PIM2 Gene [NCIt concept]
- PIM2 wt Allele [NCIt concept]
- RAB23 Gene [NCIt concept]
- RAB23 wt Allele [NCIt concept]
- RAB39B Gene [NCIt concept]
- RAB39B wt Allele [NCIt concept]
- RAB5A Gene [NCIt concept]
- RAB5A wt Allele [NCIt concept]
- RB1CC1 Gene [NCIt concept]
- RB1CC1 wt Allele [NCIt concept]
- RRAGC Gene [NCIt concept]
- RRAGC wt Allele [NCIt concept]
- RUBCN Gene [NCIt concept]
- RUBCN wt Allele [NCIt concept]
- SNAP29 Gene [NCIt concept]
- SNAP29 wt Allele [NCIt concept]
- STX17 Gene [NCIt concept]
- STX17 wt Allele [NCIt concept]
- TMEM41B Gene [NCIt concept]
- TMEM41B wt Allele [NCIt concept]
- TRIM5 Gene [NCIt concept]
- TRIM5 wt Allele [NCIt concept]
- ULK1 Gene [NCIt concept]
- ULK1 wt Allele [NCIt concept]
- ULK2 Gene [NCIt concept]
- ULK2 wt Allele [NCIt concept]
- USP13 Gene [NCIt concept]
- USP13 wt Allele [NCIt concept]
- UVRAG Gene [NCIt concept]
- UVRAG wt Allele [NCIt concept]
- VAMP8 Gene [NCIt concept]
- VAMP8 wt Allele [NCIt concept]
- VPS39 Gene [NCIt concept]
- VPS39 wt Allele [NCIt concept]
- VPS41 Gene [NCIt concept]
- VPS41 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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