Ribosomal Protein S6 Kinase Alpha-2

Preferred Label : Ribosomal Protein S6 Kinase Alpha-2;

NCIt synonyms : MAPKAP Kinase 1c; p90RSK2; RSK-3; MAPKAPK-1c; p90-RSK 2; EC 2.7.11.1; Mitogen-Activated Protein Kinase-Activated Protein Kinase 1c; RPS6KA2; MAP Kinase-Activated Protein Kinase 1c; S6K-Alpha-2; MAPK-Activated Protein Kinase 1c; Ribosomal S6 Kinase 3;

NCIt definition : Ribosomal protein S6 kinase alpha-2 (733 aa, 83 kDa) is encoded by the human RPS6KA2 gene. This protein plays a role in the modulation of transcription, cellular proliferation, differentiation, and survival.;

Details

Origin ID

C150309;

UMLS CUI

C2002840;

Automatic exact mappings (from CISMeF team)
- Ribosomal protein s6 kinase a2 [OMIM gene]
OMIM relation
- Ribosomal protein s6 kinase a2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RPS6KA2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- RPS6KA2 Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of Cell Cycle [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
is_target
- RSK1-4 Inhibitor PMD-026 [NCIt concept]

Keyword's position in hierarchy(ies) :

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