" /> Mevociclib - CISMeF





Preferred Label : Mevociclib;

NCIt synonyms : CDK7 Inhibitor SY-1365;

NCIt definition : A selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential antineoplastic activity. Upon administration, SY-1365 binds to and inhibits CDK7, thereby inhibiting CDK7-mediated signal transduction pathways. This inhibits cell growth of CDK7-overexpressing tumor cells. CDK7, a serine/threonine kinase, plays a key role in cell proliferation; CDK7 is overexpressed in a variety of tumor cell types.;

UNII : 704LW082GI;

InChIKey : SCJNYBYSTCRPAO-LXBQGUBHSA-N;

CAS number : 1816989-16-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1816989-16-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : SY-1365;

NCI Metathesaurus CUI : CL526907;

Details


Keyword's position in hierarchy(ies) : arborescence

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15/05/2024


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