5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1

Preferred Label : 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1;

NCIt synonyms : AMPK Subunit Alpha-1; Acetyl-CoA Carboxylase Kinase; HMGCR Kinase; 5'-AMP-Activated Protein Kinase, Catalytic Alpha-1 Chain; AMP-Activated Protein Kinase Catalytic Subunit Alpha-1; EC 2.7.11.31; EC 2.7.11.1; AMPK-Alpha-1; ACACA Kinase; EC 2.7.11.26; EC 2.7.11.27; Tau-Protein Kinase PRKAA1; Hydroxymethylglutaryl-CoA Reductase Kinase;

NCIt related terms : 5-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1;

NCIt definition : 5'-AMP-activated protein kinase catalytic subunit alpha-1 (559 aa, 64 kDa) is encoded by the human PRKAA1 gene. This protein is involved in the phosphorylation of metabolic enzymes, transcription regulatory proteins and microtubule-associated protein tau.;

Details

Origin ID

C116033;

UMLS CUI

C1739697;

Automatic exact mappings (from CISMeF team)
- (acetyl-CoA carboxylase) kinase [MeSH concept]
- (acetyl-CoA carboxylase) kinase [MeSH Supplementary Concept]
- (acetyl-coa carboxylase) kinase [SNOMED Notion]
- (acetyl-coenzyme A carboxylase) kinase (substance) [SNOMED CT concept]
- Protein kinase, amp-activated, catalytic, alpha-1 [OMIM gene]
- acetyl CoA carboxylase kinase A [MeSH concept]
OMIM relation
- Protein kinase, amp-activated, catalytic, alpha-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PRKAA1 protein, human [MeSH Supplementary Concept]
- PRKAA1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PRKAA1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Autophagy Regulation Pathway [NCIt concept]
- ChREBP Pathway [NCIt concept]
- Circadian Rhythm Pathway KEGG [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Insulin Resistance Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- 5'-AMP-Activated Protein Kinase [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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