" /> Betulinic Acid - CISMeF





Preferred Label : Betulinic Acid;

NCIt synonyms : Mairin; (3beta)-3-Hydroxy-lup-20(29)-en-28-oic Acid;

NCIt definition : A pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Although originally thought to exhibit specific cytotoxicity against melanoma cells, this agent has been found to be cytotoxic against non-melanoma tumor cell types including neuroectodermal and brain tumor cells.;

UNII : 4G6A18707N;

InChIKey : QGJZLNKBHJESQX-FZFNOLFKSA-N;

CAS number : 472-15-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 472-15-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : ALS-357;

Chemical formula : C30H48O3;

NSC code : 113090;

Codes from synonyms : 00061;

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15/05/2024


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