DDIT3 wt Allele

Preferred Label : DDIT3 wt Allele;

NCIt synonyms : CEBPZ; MGC4154; C/EBP Zeta Gene; CHOP; GADD153; DNA Damage Inducible Transcript 3 wt Allele; CHOP10; DNA-Damage-Inducible Transcript 3 Gene; CHOP-10; Growth Arrest- and DNA Damage-Inducible 153 Gene; CCAAT/Enhancer-Binding Protein Homologous Protein Zeta Gene; C/EBPzeta;

NCIt definition : Human DDIT3 wild-type allele is located in the vicinity of 12q13.3 and is approximately 4 kb in length. This allele, which encodes DNA damage-inducible transcript 3 protein, is involved in transcriptional suppression. Two translocations involving the gene, t(12;16)(q13;p11) with the FUS gene and t(12;22)(q13;q12) with the EWSR1 gene, are associated with myxoid liposarcoma.;

GenBank Accession Number : BC003637;

Details

Origin ID

C92540;

UMLS CUI

C2985165;

OMIM relation
- Dna damage-inducible transcript 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- Chromosomal Translocation [NCIt concept]
gene_in_chromosomal_location
- 12q13.3 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Myxoid Liposarcoma [NCIt concept]
gene_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Endoplasmic Reticulum Degradation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Negative Regulation of Cell Cycle [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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