IL24 wt Allele

Preferred Label : IL24 wt Allele;

NCIt synonyms : ST16; MDA7; Interleukin 24 wt Allele; C49A; Mob-5; FISP; IL-24; mda-7; IL10B; Melanoma Differentiation-Associated Gene 7; Suppression of Tumorigenicity 16 (Melanoma Differentiation) Gene; MOB5; Suppression of Tumorigenicity 16 Gene;

NCIt definition : Human IL24 wild-type allele is located within 1q32 and is approximately 7 kb in length. This allele, which encodes interleukin-24 protein, is involved in terminal cell differentiation and anti-proliferation. IL24 may have utility for gene-based therapy of diverse human cancers through the induction of p53 independent apoptosis.;

GenBank Accession Number : NM_006850;

Details

Origin ID

C50932;

UMLS CUI

C1705829;

OMIM relation
- Interleukin 24 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 203459184-203465879 [NCIt concept]
gene_in_chromosomal_location
- 1q32 [NCIt concept]
gene_is_element_in_pathway
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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