PR Domain Zinc Finger Protein 4

Preferred Label : PR Domain Zinc Finger Protein 4;

NCIt synonyms : PFM1; PR-Domain Zinc Finger Protein 4; PR-Domain Zinc-Finger Protein PFM1; PR Domain Containing 4 Protein; PRDM4; PR Domain-Containing Protein 4; PR-Domain Zinc Finger Protein-4;

NCIt definition : PR domain zinc finger protein 4 (801 aa, 88 kDa) is encoded by the human PRDM4 gene. This protein plays a role in transcriptional regulation, cell cycle progression, cell proliferation and signal transduction.;

NCIt note : PR-Domain Zinc Finger Protein 4 contains a PR-domain, a SET domain, and multiple zinc finger motifs. PR-domain transcription factors are typically involved in cell differentiation.;

Details

Origin ID

C34093;

UMLS CUI

C1335250;

OMIM relation
- Pr domain-containing protein 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- PRDM4 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- SET Domain [NCIt concept]
gene_product_is_element_in_pathway
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- DNA Binding [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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