C2H2 Zinc Finger

Preferred Label : C2H2 Zinc Finger;

NCIt definition : One of three structural motifs observed in DNA binding domains of zinc proteins. Domains in DNA- and RNA-binding proteins that contain amino acids which are folded into a single structural unit around a zinc atom that links two cysteines and two histidines. Each finger is postulated to recognize a specific sequence of about five nucleotide pairs. Originally identified in the TFIIIA transcription factor, it is also known as the C2H2 zinc finger.;

Details

Origin ID

C13294;

UMLS CUI

C1511358;

Automatic exact mappings (from CISMeF team)
- CYS2-HIS2 Zinc Fingers [MeSH Descriptor]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
UMLS correspondences (same concept)
- CYS2-HIS2 Zinc Fingers [MeSH Descriptor]
is_structural_domain_or_motif_of_gene_product
- ACTB/GLI1 Fusion Protein [NCIt concept]
- AT-Rich Interactive Domain-Containing Protein 2 [NCIt concept]
- ATM Interactor [NCIt concept]
- Activity-Dependent Neuroprotector Homeobox Protein [NCIt concept]
- Aprataxin [NCIt concept]
- B-Cell Lymphoma 6 Protein [NCIt concept]
- B-Cell Lymphoma/Leukemia 11A [NCIt concept]
- B-Cell Lymphoma/Leukemia 11B [NCIt concept]
- Breast Cancer Type 1 Susceptibility Protein [NCIt concept]
- Bromodomain-Containing Protein 1 [NCIt concept]
- CBFA2T3/GLIS2 Fusion Protein [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-1 [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-2 [NCIt concept]
- DNA-Binding Protein Ikaros [NCIt concept]
- E3 SUMO-Protein Ligase EGR2 [NCIt concept]
- E3 SUMO-Protein Ligase ZNF451 [NCIt concept]
- Early Growth Response Protein 1 [NCIt concept]
- Early Growth Response Protein 3 [NCIt concept]
- Forkhead Box Protein P1 [NCIt concept]
- Forkhead Box Protein P3 [NCIt concept]
- Forkhead Box Protein P4 [NCIt concept]
- GLI Family Protein [NCIt concept]
- Histone-Lysine N-Methyltransferase MECOM [NCIt concept]
- Histone-Lysine N-Methyltransferase PRDM16 [NCIt concept]
- Insulinoma-Associated Protein 2 [NCIt concept]
- Juxtaposed With Another Zinc Finger Protein 1 [NCIt concept]
- Krueppel-Like Factor 1 [NCIt concept]
- Krueppel-Like Factor 17 [NCIt concept]
- Krueppel-Like Factor 2 [NCIt concept]
- Krueppel-Like Factor 3 [NCIt concept]
- Krueppel-Like Factor 4 [NCIt concept]
- Krueppel-Like Factor 5 [NCIt concept]
- Krueppel-Like Factor 6 [NCIt concept]
- MECOM Protein Isoform Evi-1a [NCIt concept]
- Myc-Associated Zinc Finger Protein [NCIt concept]
- PHD Finger Protein 20 [NCIt concept]
- POZ-, AT Hook-, and Zinc Finger-Containing Protein 1 [NCIt concept]
- PR Domain Zinc Finger Protein 1 [NCIt concept]
- PR Domain Zinc Finger Protein 2 [NCIt concept]
- PR Domain Zinc Finger Protein 4 [NCIt concept]
- PR Domain Zinc Finger Protein 5 [NCIt concept]
- Paternally-Expressed Gene 3 Protein [NCIt concept]
- Pogo Transposable Element With ZNF Domain [NCIt concept]
- Polycomb Complex Protein BMI-1 [NCIt concept]
- RNA-Binding Protein 10 [NCIt concept]
- RNA-Binding Protein 5 [NCIt concept]
- Ras-Responsive Element-Binding Protein 1 [NCIt concept]
- Sal-Like Protein 2 [NCIt concept]
- Sal-Like Protein 4 [NCIt concept]
- TRAF Family Member-Associated NF-Kappa-B Activator [NCIt concept]
- Transcription Factor HIVEP3 [NCIt concept]
- Transcription Factor Sp1 [NCIt concept]
- Transcription Factor Sp3 [NCIt concept]
- Transcription Factor Sp4 [NCIt concept]
- Transcriptional Regulator Kaiso [NCIt concept]
- Transcriptional Repressor Protein YY1 [NCIt concept]
- Transcriptional-Regulating Factor 1 [NCIt concept]
- Truncated Glioma-Associated Oncogene Homolog 1 Protein [NCIt concept]
- Zinc Finger CCCH Domain-Containing Protein 7B [NCIt concept]
- Zinc Finger E-Box-Binding Homeobox 2 [NCIt concept]
- Zinc Finger Homeobox Protein 3 [NCIt concept]
- Zinc Finger Imprinted 2 [NCIt concept]
- Zinc Finger Protein 148 [NCIt concept]
- Zinc Finger Protein 217 [NCIt concept]
- Zinc Finger Protein 224 [NCIt concept]
- Zinc Finger Protein 281 [NCIt concept]
- Zinc Finger Protein 292 [NCIt concept]
- Zinc Finger Protein 331 [NCIt concept]
- Zinc Finger Protein 341 [NCIt concept]
- Zinc Finger Protein 350 [NCIt concept]
- Zinc Finger Protein 362 [NCIt concept]
- Zinc Finger Protein 384 [NCIt concept]
- Zinc Finger Protein 385B [NCIt concept]
- Zinc Finger Protein 42 Homolog [NCIt concept]
- Zinc Finger Protein 429 [NCIt concept]
- Zinc Finger Protein 444 [NCIt concept]
- Zinc Finger Protein 479 [NCIt concept]
- Zinc Finger Protein 496 [NCIt concept]
- Zinc Finger Protein 521 [NCIt concept]
- Zinc Finger Protein 532 [NCIt concept]
- Zinc Finger Protein 608 [NCIt concept]
- Zinc Finger Protein 638 [NCIt concept]
- Zinc Finger Protein 652 [NCIt concept]
- Zinc Finger Protein 678 [NCIt concept]
- Zinc Finger Protein 687 [NCIt concept]
- Zinc Finger Protein 700 [NCIt concept]
- Zinc Finger Protein 703 [NCIt concept]
- Zinc Finger Protein 717 [NCIt concept]
- Zinc Finger Protein 750 [NCIt concept]
- Zinc Finger Protein 768 [NCIt concept]
- Zinc Finger Protein 793 [NCIt concept]
- Zinc Finger Protein AEBP2 [NCIt concept]
- Zinc Finger Protein Aiolos [NCIt concept]
- Zinc Finger Protein DPF3 [NCIt concept]
- Zinc Finger Protein GLI1 [NCIt concept]
- Zinc Finger Protein GLI2 [NCIt concept]
- Zinc Finger Protein GLI3 [NCIt concept]
- Zinc Finger Protein GLIS1 [NCIt concept]
- Zinc Finger Protein GLIS2 [NCIt concept]
- Zinc Finger Protein GLIS3 [NCIt concept]
- Zinc Finger Protein Gfi-1 [NCIt concept]
- Zinc Finger Protein Gfi-1b [NCIt concept]
- Zinc Finger Protein Helios [NCIt concept]
- Zinc Finger Protein PLAG1 [NCIt concept]
- Zinc Finger Protein PLAGL1 [NCIt concept]
- Zinc Finger Protein PLAGL2 [NCIt concept]
- Zinc Finger Protein SNAI1 [NCIt concept]
- Zinc Finger Protein SNAI2 [NCIt concept]
- Zinc Finger Protein Ubi-D4 [NCIt concept]
- Zinc Finger Protein ZFPM1 [NCIt concept]
- Zinc Finger Protein ZFPM2 [NCIt concept]
- Zinc Finger Protein ZIC 1 [NCIt concept]
- Zinc Finger Protein ZIC 2 [NCIt concept]
- Zinc Finger Protein ZIC 3 [NCIt concept]
- Zinc Finger Protein ZIC 4 [NCIt concept]
- Zinc Finger Transcription Factor Trps1 [NCIt concept]
- Zinc Finger Translocation-Associated Protein [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 16 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 17 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 2 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 20 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 38 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 46 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 48 [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 7A [NCIt concept]
- Zinc Finger and BTB Domain-Containing Protein 7B [NCIt concept]
- Zinc Finger and SCAN Domain-Containing Protein 30 [NCIt concept]

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