Protein Phosphatase 1 Regulatory Subunit 15A

Preferred Label : Protein Phosphatase 1 Regulatory Subunit 15A;

NCIt synonyms : Growth Arrest and DNA Damage-Inducible Protein GADD34; Myeloid Differentiation Primary Response Protein MyD116 Homolog;

NCIt definition : Protein phosphatase 1 regulatory subunit 15A (674 aa, 73 kDa) is encoded by the human PPP1R15A gene. This protein is involved in both signaling and phosphatase recruitment.;

NCIt note : Protein phosphatase 1 regulatory subunit 15A plays a role in endoplasmic reticulum stress-induced signaling. (PNAS 2011; 108 :6561-6566.);

Details

Origin ID

C97253;

UMLS CUI

C3273306;

OMIM relation
- Protein phosphatase 1, regulatory subunit 15a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- PPP1R15A Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_is_element_in_pathway
- BMP Receptor Signaling Pathway [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Stress Response [NCIt concept]
- Negative Regulation of Cell Cycle [NCIt concept]
- Translational Activation [NCIt concept]

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