Histone Deacetylation

Preferred Label : Histone Deacetylation;

NCIt definition : Histone Deacetylation is the covalent post-translational enzymatic removal of acetyl group(s) from a histone protein. By exposing cationic sites on the protein that promote ionic interaction with the negatively charged DNA backbone, Histone Deacetylation induces DNA condensation and regulates genetic functions, such as transcription. (NCI);

Details

Origin ID

C40580;

UMLS CUI

C1156201;

Currated CISMeF NLP mapping
- histone deacetylation [GO term]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- histone deacetylation [GO term]
biological_process_involves_gene_product
- Histone Deacetylase [NCIt concept]
- Histone Deacetylase 1 [NCIt concept]
- Histone Deacetylase 10 [NCIt concept]
- Histone Deacetylase 11 [NCIt concept]
- Histone Deacetylase 2 [NCIt concept]
- Histone Deacetylase 3 [NCIt concept]
- Histone Deacetylase 4 [NCIt concept]
- Histone Deacetylase 5 [NCIt concept]
- Histone Deacetylase 6 [NCIt concept]
- Histone Deacetylase 7 [NCIt concept]
- Histone Deacetylase 8 [NCIt concept]
- Histone Deacetylase 9 [NCIt concept]
- Inhibitor of Growth Protein 2 [NCIt concept]
- Zinc Finger MYM-Type Protein 3 [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
- Post-Translational Regulation [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- Tributyrin [NCIt concept]
process_involves_gene
- HDAC10 Gene [NCIt concept]
- HDAC10 wt Allele [NCIt concept]
- HDAC11 Gene [NCIt concept]
- HDAC11 wt Allele [NCIt concept]
- HDAC7 Gene [NCIt concept]
- HDAC7 wt Allele [NCIt concept]
- HDAC9 Gene [NCIt concept]
- HDAC9 wt Allele [NCIt concept]
- ING2 Gene [NCIt concept]
- ING2 wt Allele [NCIt concept]
- ZMYM3 Gene [NCIt concept]
- ZMYM3 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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