Histone Deacetylase 8

Preferred Label : Histone Deacetylase 8;

NCIt synonyms : EC 3.5.1.98; HDAC8; HD8; Histone Deacetylase-Like 1;

NCIt definition : Histone deacetylase 8 (377 aa, 24 kDa) is encoded by the human HDAC8 gene. This protein is involved in the deacetylation of core histones.;

Details

Origin ID

C113607;

UMLS CUI

C1438985;

Automatic exact mappings (from CISMeF team)
- Histone deacetylase 8 [OMIM gene]
- histone deacetylase 8 [ORDO Gene]
- histone deacetylase 8 [HGNC gene]
OMIM relation
- Histone deacetylase 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- HDAC8 protein, human [MeSH concept]
- HDAC8 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HDAC8 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Progression [NCIt concept]
- Chromatin Remodeling [NCIt concept]
- Deacetylation [NCIt concept]
- Developmental Process [NCIt concept]
- Histone Deacetylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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